# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5144250 | F | Leishmanicidal activity against axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 assessed as reduction of proliferation of amastigotes incubated for 24 hrs by propidium iodide staining based flow cytometry | Leishmania infantum | 16 | organism-based format | Scientific Literature | ||
2. | ALA5144251 | T | Cytotoxicity against human THP-1 cells assessed as reduction in cell proliferation incubated for 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
3. | ALA5144252 | T | Selectivity index, ratio of LC50 for cytotoxicity against human THP-1 cells to EC50 of leishmanicidal activity against axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 | 16 | cell-based format | Scientific Literature | |||
4. | ALA5144253 | F | Leishmanicidal activity against GFP-expressing axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human THP-1 macrophage cells assessed as reduction in intracellular amastigotes incubated for 48 hrs by propidium iodide staining based flow cytometry | Leishmania infantum | 5 | organism-based format | Scientific Literature |