# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5108594 | B | Non competitive type inhibition of human TS assessed as inhibition constant using varying levels of mTHF as substrate by UV-Vis spectroscopy based analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
2. | ALA5108595 | B | Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP as substrate by UV-Vis spectroscopy based analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
3. | ALA5108596 | A | Drug uptake in human IGROV-1 cell assessed as drug level in cytosol at 5 uM incubated for 30 mins at 37 degC in RPMI media with 10% FBS by LC-MS/MS analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
4. | ALA5108597 | A | Drug uptake in human IGROV-1 cell assessed as drug level in vesicle at 5 uM incubated for 30 mins at 37 degC in RPMI media with 10% FBS by LC-MS/MS analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
5. | ALA5108598 | A | Drug uptake in human IGROV-1 cell assessed as drug level in extracellular at 5 uM incubated for 30 mins at 37 degC in RPMI media with 10% FBS by LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5108599 | A | Drug uptake in human IGROV-1 cell assessed as drug level in cytosol at 5 uM incubated for 30 mins at 4 degC in RPMI media with 10% FBS by LC-MS/MS analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
7. | ALA5108600 | A | Drug uptake in human IGROV-1 cell assessed as vesicle at 5 uM incubated for 30 mins at 4 degC in RPMI media with 10% FBS by LC-MS/MS analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
8. | ALA5108601 | A | Drug uptake in human IGROV-1 cell assessed as extracellular at 5 uM incubated for 30 mins at 4 degC in RPMI media with 10% FBS by LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5108602 | F | Cytotoxicity against human IGROV-1 cells assessed as growth inhibition at 0.1 to 2.5 uM measured upto 72 hrs by crystal violet dye assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA5108603 | F | Cytotoxicity against human TOV112D cells assessed as growth inhibition at 0.1 to 2.5 uM measured upto 72 hrs by crystal violet dye assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA5108604 | B | Displacement of [3H]FA binding to FRalpha in human IGROV-1 assessed as radioligand uptake at 5 uM measured after 10 mins by competitive binding assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5108605 | B | Displacement of [3H]FA binding to FRalpha in human OAW-28 assessed as radioligand uptake at 5 uM measured after 10 mins by competitive binding assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5108606 | B | Displacement of [3H]FA from FRalpha in human IGROV-1 cell surface at 5 uM by flow cytometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA5108610 | B | Reduction in intracellular TS activity in human IGROV-1 cells measured at 1.25 uM by tritium release assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5108611 | B | Reduction in intracellular TS activity in human IGROV-1 cells measured at 2.5 uM by tritium release assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA5108612 | B | Reduction in intracellular TS activity in human IGROV-1 cells assessed as residual activity measured at 5 uM by tritium release assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |