# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5129307 | T | Cytotoxicity against human Huh7-J20 cells assessed as reduction in cell viability by MTS assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
2. | ALA5129308 | F | Antiviral activity against Huh 7.5 cell culture derived HCV genotype 2a (JFH-AM71) infected in human Huh7-J20 cells assessed as inhibition of viral replication at 100 uM treated for 72 hrs by SEAP reporter gene assay relative to control | Hepacivirus hominis | 5 | organism-based format | Scientific Literature | ||
3. | ALA5129310 | F | Antiviral activity against Huh 7.5 cell culture derived HCV genotype 2a (JFH-AM71) infected in human Huh7-J20 cells assessed as inhibition of viral replication treated for 72 hrs by SEAP reporter gene assay | Hepacivirus hominis | 5 | organism-based format | Scientific Literature | ||
4. | ALA5129311 | T | Selectivity index, ratio of CC50 for cytotoxicity against human Huh-7 J20 cells assessed as reduction in cell viability to IC50 for antiviral activity against Huh 7.5 cell culture derived HCV genotype 2a (JFH-AM71) infected in human Huh7-J20 cells assessed as inhibition of viral replication | 5 | cell-based format | Scientific Literature | |||
5. | ALA5129312 | T | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability by MTS assay | Chlorocebus sabaeus | 16 | cell-based format | Scientific Literature | ||
6. | ALA5129313 | T | Cytotoxicity against human Huh7.5 cells assessed as reduction in cell viability by MTS assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
7. | ALA5129314 | F | Antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in human Huh7.5 cells assessed as inhibition of viral replication by measuring ZIKV E glycoprotein level at 100 uM incubated for 3 days by ELISA analysis relative to control | Zika virus | 14 | organism-based format | Scientific Literature | ||
8. | ALA5129315 | F | Antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in African green monkey Vero cells assessed as inhibition of viral replication by measuring ZIKV E glycoprotein level at 100 uM incubated for 3 days by ELISA analysis relative to control | Zika virus | 14 | organism-based format | Scientific Literature | ||
9. | ALA5129318 | F | Antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in human Huh7.5 cells assessed as reduction in viral titer incubated for 3 days by plaque assay | Zika virus | 2 | organism-based format | Scientific Literature | ||
10. | ALA5129319 | F | Antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in African green monkey Vero cells assessed as reduction in viral titer incubated for 3 days by plaque assay | Zika virus | 2 | organism-based format | Scientific Literature | ||
11. | ALA5129320 | F | Antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in human Huh7.5 cells assessed as reduction in viral titer at 50 to 100 uM incubated for 3 days by plaque assay relative to control | Zika virus | 1 | organism-based format | Scientific Literature | ||
12. | ALA5129321 | F | Antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in African green monkey Vero cells assessed as reduction in viral titer at 50 to 100 uM incubated for 3 days by plaque assay relative to control | Zika virus | 1 | organism-based format | Scientific Literature | ||
13. | ALA5129322 | T | Selectivity index, ratio of CC50 for cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability to IC50 for antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in African green monkey Vero cells assessed as reduction in viral titer | 2 | cell-based format | Scientific Literature | |||
14. | ALA5129323 | T | Selectivity index, ratio of CC50 for cytotoxicity against human Huh7.5 cells assessed as reduction in cell viability to IC50 for antiviral activity against Zika virus H/PAN/2016/BEI-259634 infected in human Huh7.5 cells assessed as reduction in viral titer | 2 | cell-based format | Scientific Literature |