# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5166170 | F | Antiviral activity against ZIKV H/PF/2013 infected in human A549 cells assessed as reduction in number of infected cells at 80 uM measured after 24 hrs post infection by immunofluorescence microscopic analysis relative to control | Zika virus | 2 | ALA5154892 | organism-based format | Scientific Literature | |
2. | ALA5166171 | T | Cytotoxicity against human A549 cells assessed as cell viability upto 80 uM and measured after 24 to 48 hrs by PrestoBlue dye based microplate reader analysis | Homo sapiens | 4 | ALA5154892 | cell-based format | Scientific Literature | |
3. | ALA5166172 | F | Antiviral activity against Zika virus infected in human A549 cells assessed as reduction in luciferase activity at 20 uM measured up to 48 hrs post infection by luciferase assay | Zika virus | 4 | ALA5154892 | organism-based format | Scientific Literature | |
4. | ALA5166173 | B | Inhibition of bovine thrombin at 100 uM using Tos-Gly-Pro-Arg-AMC as substrate by fluorescence plate reader analysis | Bos taurus | 9 | ALA5154892 | single protein format | Scientific Literature | |
5. | ALA5166174 | F | Antiviral activity against ZIKV H/PF/2013 infected in human A549 cells assessed as change in number of infected cells after secondary infection at 80 uM measured after 48 hrs post infection by immunofluorescence microscopic analysis | Zika virus | 1 | ALA5154892 | organism-based format | Scientific Literature | |
6. | ALA5166175 | B | Binding affinity to Zika virus NS2B-NS3 protease using Phac-Leu-Lys-Lys-Arg-AMC as substrate measured immediately upto 10 mins by fluorogenic assay | Zika virus | 29 | ALA5154892 | assay format | Scientific Literature | |
7. | ALA5166176 | B | Binding affinity to West Nile virus NSB2 (52 to 96 amino acids)-NS3 (1 to 184 amino acids) protease using Phac-Leu-Lys-Lys-Arg-AMC as substrate measured immediately upto 10 mins by fluorogenic assay | West Nile virus | 29 | ALA5154892 | assay format | Scientific Literature | |
8. | ALA5166177 | B | Inhibition of porcine trypsin at 100 uM using Mes-D-Arg-Gly-Arg-AMC a substrate by fluorescence plate reader analysis | Sus scrofa | 9 | ALA5154892 | single protein format | Scientific Literature | |
9. | ALA5166179 | F | Antiviral activity against ZIKV H/PF/2013 infected in human A549 cells assessed as reduction in extracellular virus titer in cell supernatant at 80 uM measured after 24 hrs post infection by plaque assay based crystal violet staining analysis | Zika virus | 2 | ALA5154892 | organism-based format | Scientific Literature | |
10. | ALA5166180 | F | Antiviral activity against ZIKV H/PF/2013 infected in human A549 cells assessed as reduction in extracellular virus titer in cell supernatant at 80 uM measured after 48 hrs post infection by plaque assay based crystal violet staining analysis | Zika virus | 2 | ALA5154892 | organism-based format | Scientific Literature | |
11. | ALA5166181 | F | Antiviral activity against ZIKV H/PF/2013 infected in human A549 cells assessed as reduction in intracellular virus titer at 80 uM measured after 24 hrs post infection by plaque assay based crystal violet staining analysis | Zika virus | 2 | ALA5154892 | organism-based format | Scientific Literature | |
12. | ALA5166182 | F | Antiviral activity against ZIKV H/PF/2013 infected in human A549 cells assessed as reduction in intracellular virus titer at 80 uM measured after 48 hrs post infection by plaque assay based crystal violet staining analysis | Zika virus | 2 | ALA5154892 | organism-based format | Scientific Literature |