# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5118966 | Binding | Inhibition of recombinant human MMP-1 using peptide substrate by ELISA | Homo sapiens | 3 | ALA5113513 | single protein format | Scientific Literature | |
2. | ALA5118967 | Binding | Inhibition of recombinant human MMP-2 using peptide substrate by ELISA | Homo sapiens | 5 | ALA5113513 | single protein format | Scientific Literature | |
3. | ALA5118968 | Binding | Inhibition of recombinant human MMP-3 using peptide substrate by ELISA | Homo sapiens | 3 | ALA5113513 | single protein format | Scientific Literature | |
4. | ALA5118969 | Binding | Inhibition of recombinant human MMP-8 using peptide substrate by ELISA | Homo sapiens | 3 | ALA5113513 | single protein format | Scientific Literature | |
5. | ALA5118970 | Binding | Inhibition of recombinant human MMP-9 using peptide substrate by ELISA | Homo sapiens | 5 | ALA5113513 | single protein format | Scientific Literature | |
6. | ALA5118971 | Binding | Inhibition of recombinant human MMP-12 using peptide substrate by ELISA | Homo sapiens | 3 | ALA5113513 | single protein format | Scientific Literature | |
7. | ALA5118972 | Binding | Inhibition of recombinant human MMP-13 using peptide substrate by ELISA | Homo sapiens | 3 | ALA5113513 | single protein format | Scientific Literature | |
8. | ALA5118973 | Binding | Inhibition of recombinant human TACE using peptide substrate by ELISA | Homo sapiens | 3 | ALA5113513 | assay format | Scientific Literature | |
9. | ALA5118974 | Functional | Inhibition of cell invasion in mouse B16-F10 cells at 100 uM by Matrigel invasion assay | Mus musculus | 1 | ALA5113513 | cell-based format | Scientific Literature | |
10. | ALA5118975 | ADME | Half life in Sprague-Dawley rats at 50 mg/kg, iv | Rattus norvegicus | 1 | ALA5113513 | organism-based format | Scientific Literature | |
11. | ALA5118976 | ADME | Half life in Sprague-Dawley rats at 150 mg/kg, po | Rattus norvegicus | 1 | ALA5113513 | organism-based format | Scientific Literature | |
12. | ALA5118977 | ADME | Half life in Sprague-Dawley rats at 150 mg/kg, ip | Rattus norvegicus | 1 | ALA5113513 | organism-based format | Scientific Literature | |
13. | ALA5118978 | Functional | Antimetastatic activity in mouse B16-F10 xenografted C57BL mouse lung metastasis model assessed as reduction in metastasis at 50 mg/kg, ip | Mus musculus | 1 | ALA5113513 | organism-based format | Scientific Literature | |
14. | ALA5118979 | Functional | Antimetastatic activity in po dosed mouse B16-F10 xenografted C57BL mouse lung metastasis model assessed as reduction in metastasis | Mus musculus | 1 | ALA5113513 | organism-based format | Scientific Literature | |
15. | ALA5118980 | Functional | Antimetastatic activity in mouse B16-F10 xenografted C57BL mouse melanoma model assessed as reduction in metastasis loci at 12.5 to 50 mg/kg, ip | Mus musculus | 1 | ALA5113513 | organism-based format | Scientific Literature | |
16. | ALA5118981 | Functional | Antitumor activity against SCID mouse with human tumor cell orthotopic implantation assessed as reduction in tumor growth at 50 mg/kg, ip for 6 weeks | Mus musculus | 1 | ALA5113513 | organism-based format | Scientific Literature | |
17. | ALA5118982 | Functional | Antimetastatic activity in SCID mouse with human tumor cell orthotopic implantation assessed as reduction in tumor metastasis at 50 mg/kg, ip for 6 weeks | Mus musculus | 1 | ALA5113513 | organism-based format | Scientific Literature |