| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5156738 | T | Hemolytic activity in human RBC assessed as hemolysis incubated for 2 hrs by spectrophotometer analysis | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 2. | ALA5156739 | F | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC BAA-1556 incubated for 24 hrs by microtiter plate method | Staphylococcus aureus | 39 | organism-based format | Scientific Literature | ||
| 3. | ALA5156740 | F | Antibacterial activity against Staphylococcus aureus ATCC 29213 incubated for 24 hrs by microtiter plate method | Staphylococcus aureus | 39 | organism-based format | Scientific Literature | ||
| 4. | ALA5156741 | F | Antibacterial activity against Pseudomonas aeruginosa ATCC 27883 incubated for 24 hrs by microtiter plate method | Pseudomonas aeruginosa | 39 | organism-based format | Scientific Literature | ||
| 5. | ALA5156742 | F | Antibacterial activity against Escherichia coli ATCC 25922 incubated for 24 hrs by microtiter plate method | Escherichia coli | 39 | organism-based format | Scientific Literature | ||
| 6. | ALA5156780 | B | Membrano-lytic effect in bacterial inner membrane mimic DOPC/DOPG (7:3) large unilamellar vesicles assessed as calcein leakage measured upto 100 mins for every 10 mins by multimode microplate reader assay | 5 | cell membrane format | Scientific Literature | |||
| 7. | ALA5156781 | T | Cytotoxicity against HEK293 assessed as cell viability measured after 24 hrs by microplate spectrophotometer analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5156782 | T | Cytotoxicity against human MRC-5 assessed as cell viability measured after 24 hrs by microplate spectrophotometer analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5156783 | F | Cytotoxicity against human HPRGC10 assessed as cell viability measured after 24 hrs by microplate spectrophotometer analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5156788 | F | Bactericidal activity against Escherichia coli ATCC BAA-2452 assessed as time required for complete reduction of bacterial growth at MIC by counting formed colonies | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA5156789 | F | Bactericidal activity against Escherichia coli ATCC BAA-2452 assessed as time required for complete reduction of bacterial growth at 4 times MIC by counting formed colonies | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA5156790 | F | Bactericidal activity against methicillin resistant Staphylococcus aureus ATCC BAA-1556 assessed as time required for complete reduction of bacterial growth at MIC by counting formed colonies | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 13. | ALA5156791 | F | Bactericidal activity against methicillin resistant Staphylococcus aureus ATCC BAA-1556 assessed as time required for complete reduction of bacterial growth at 4 times MIC by counting formed colonies | Staphylococcus aureus | 7 | organism-based format | Scientific Literature | ||
| 14. | ALA5156795 | B | Membrano-lytic effect in mammalian membrane mimic DOPC/cholesterol (10:1) large unilamellar vesicles assessed as calcein leakage measured at 5 to 50 microg/ml measured upto 100 mins for every 10 mins by multimode microplate reader assay | 5 | cell membrane format | Scientific Literature | |||
| 15. | ALA5156796 | B | Membrano-lytic effect in mammalian membrane mimic DOPC/cholesterol (10:1) large unilamellar vesicles assessed as calcein leakage measured at 50 microg/ml measured upto 100 mins for every 10 mins by multimode microplate reader assay | 5 | cell membrane format | Scientific Literature | |||
| 16. | ALA5156800 | B | Membrano-lytic effect in cytoplasmic membrane of methicillin resistant Staphylococcus aureus ATCC BAA-1556 assessed as disruption by measuring propidium iodide fluorescence at MIC incubated for 1 hr by FACscan flow cytometer analysis | Staphylococcus aureus | 2 | subcellular format | Scientific Literature | ||
| 17. | ALA5156804 | A | Proteolytic stability in human plasma at 100 uM incubated for 30 mins by Q-TOF LC/MS analysis relative to control | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
| 18. | ALA5156805 | A | Proteolytic stability in human plasma at 100 uM incubated for 24 hrs by Q-TOF LC/MS analysis relative to control | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
| 19. | ALA5156806 | B | Induction of membrane disruption in bacterial inner membrane mimic DOPC/DOPG (7:3) large unilamellar vesicles assessed as decrease in particle size of liposome at 1:1 compound to lipid ratio measured after 24 hrs by dynamic light scattering analysis | 2 | cell membrane format | Scientific Literature | |||
| 20. | ALA5156811 | B | Membrano-lytic effect in cytoplasmic membrane of methicillin resistant Staphylococcus aureus ATCC BAA-1556 assessed as disruption by measuring propidium iodide fluorescence incubated for 1 hr by FACscan flow cytometer analysis | Staphylococcus aureus | 4 | subcellular format | Scientific Literature |
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