# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5161275 | B | Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced Ca2+ influx at 10 uM incubated for 30 mins by FLIPR method | Homo sapiens | 83 | cell-based format | Scientific Literature | ||
2. | ALA5161276 | B | Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced Ca2+ influx incubated for 30 mins by FLIPR method | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
3. | ALA5161277 | B | Antagonist activity at human TRPV1 expressed in CHO cells assessed as low pH-induced Ca2+ influx at 10 uM incubated for 30 mins at pH 5 by FLIPR method | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
4. | ALA5161278 | F | Analgesic activity against capsaicin-induced pain mouse model assessed as reduction in time spent on foot licking behaviour at 10 mg/kg, ip administered 30 mins prior to capsaicin stimulation and measured after 5 mins | Mus musculus | 8 | organism-based format | Scientific Literature | ||
5. | ALA5161279 | F | Antinociceptive activity in mouse assessed as reduction in acetic acid induced writhing response at 10 mg/kg, ip administered 30 mins prior to acetic acid administration and measured every 15 mins by abdominal constriction test | Mus musculus | 6 | organism-based format | Scientific Literature | ||
6. | ALA5161280 | F | Antinociceptive activity against thermal-induced nociception mouse model assessed as increase in tail withdrawal latency at 10 mg/kg, ip measured after 30 mins by tail flick test | Mus musculus | 8 | organism-based format | Scientific Literature |