| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5159800 | B | Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by substrate addition measured by fluorescence assay | Homo sapiens | 34 | protein complex format | Scientific Literature | ||
| 2. | ALA5159801 | F | Antiproliferative activity against human RPMI-8226 cells after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA5159802 | F | Antiproliferative activity against human MM1.S cells after 72 hrs by MTS assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA5159803 | F | Antiproliferative activity against human MV4-11 cells after 72 hrs by MTS assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA5159804 | B | Inhibition of chymotrypsin-like activity of 20S proteasome in human MM1.S cells assessed as accumulation of polyubiquitinated proteins at 10 to 1000 nM and measured by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA5159805 | A | Stability of the compound in mouse blood assessed as half-life measured by LC-MS/MS analysis | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
| 7. | ALA5159806 | F | In vivo inhibition of chymotrypsin-like activity of 20S proteasome in ICR mouse at 5 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature |
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