# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5168032 | B | Binding affinity to MBP-tagged human recombinant AF9 (487 to 568 residues) incubated for 40 mins by measuring fluorescence polarization by microplate reader method | Homo sapiens | 14 | single protein format | Scientific Literature | ||
2. | ALA5168033 | B | Binding affinity to MBP-tagged human recombinant ENL (489 to 559 residues) incubated for 40 mins by measuring fluorescence polarization by microplate reader method | Homo sapiens | 14 | single protein format | Scientific Literature | ||
3. | ALA5168034 | F | Anticancer activity against human MOLM-13 cells harbouring MLL-AF9 assessed as inhibition of cell growth treated for 8 days measured by CCK-8 kit method | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
4. | ALA5168035 | F | Anticancer activity against human KOPN-8 cells harbouring MLL-ENL assessed as inhibition of cell growth treated for 8 days measured by CCK-8 kit method | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
5. | ALA5168036 | F | Anticancer activity against human RS4-11 cells assessed as inhibition of cell growth treated for 8 days measured by CCK-8 kit method | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
6. | ALA5168037 | F | Anticancer activity against human MV4-11 cells assessed as inhibition of cell growth treated for 8 days measured by CCK-8 kit method | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
7. | ALA5168038 | F | Anticancer activity against human K562 cells assessed as inhibition of cell growth treated for 8 days measured by CCK-8 kit method | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
8. | ALA5168039 | F | Potency index, ratio of (S)-N-((S)-1-((S)-3-amino-1-((S)-1-((S)-2-(1-(cyclohexylmethyl)-4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-cyclopentyl-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-1-(4-methylpentanoyl)pyrrolidine-2-carboxamide IC50 to test compound IC50 for anticancer activity against human MOLM-13 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
9. | ALA5168040 | F | Potency index, ratio of (S)-N-((S)-1-((S)-3-amino-1-((S)-1-((S)-2-(1-(cyclohexylmethyl)-4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-cyclopentyl-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-1-(4-methylpentanoyl)pyrrolidine-2-carboxamide IC50 to test compound IC50 for anticancer activity against human KOPN-8 cells | Homo sapiens | 6 | cell-based format | Scientific Literature |