# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5152738 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA5152739 | B | Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA5152740 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as binding constant by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
4. | ALA5152741 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as change in enthalpy by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA5152742 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as change in entropy by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA5152743 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as gibbs free energy change by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
7. | ALA5152744 | F | Induction of triglyceride level in Sprague-Dawley rat at 200 mg/kg in diet for 7 days (Rvb = 89 +/- 10 mg/dl) | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
8. | ALA5152746 | F | Induction of triglyceride level in Sprague-Dawley rat at 200 mg/kg in diet for 7 days relative to control (Rvb = 0 %) | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
9. | ALA5152748 | F | Upregulation of RBP1 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA5152749 | F | Upregulation of STRA6 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA5152750 | F | Upregulation of LRAT gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA5152751 | F | Upregulation of RDH10 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA5152752 | F | Upregulation of RARB gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA5152753 | F | Upregulation of RARG gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5152754 | F | Upregulation of CRABP2 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA5152755 | F | Downregulation of LOR gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA5152756 | F | Downregulation of ACER1 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA5152757 | F | Downregulation of MCM7 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA5152758 | F | Effect on CYP26B1 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA5152759 | F | Effect on RDH11 gene expression in human organotypic epithelial cells at 0.2 uM incubated for 9 days with replacement of fresh compounds every other day by qPCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |