| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5098674 | B | Inhibition of CDK9 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of 5 mM ATP by plate reader analysis | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 2. | ALA5098675 | B | Inhibition of CDK9 in human MCF7 cells assessed as reduction in RNA polymerase II phosphorylation at ser2 residue incubated for 6 hrs by fluorescence based assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 3. | ALA5098676 | B | Activation of caspase 3/7 in human MV4-11 cells incubated for 6 hrs by Caspase-Glo 3/7 reagent based microplate reader analysis | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 4. | ALA5098677 | P | Lipophilicity, logD of the compound in octanol/buffer at pH 7.4 by shake flask method | 38 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA5098678 | P | Solubility of the compound in phosphate buffer at pH 7.4 | 37 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA5098694 | A | Intrinsic clearance in rat hepatocytes assessed per 10^6 cells | Rattus norvegicus | 32 | cell-based format | Scientific Literature | ||
| 7. | ALA5098695 | A | Intrinsic clearance in human liver microsomes assessed per mg protein | Homo sapiens | 32 | microsome format | Scientific Literature | ||
| 8. | ALA5098696 | A | Intrinsic clearance in cryopreserved human hepatocytes assessed per 10^6 cells | Homo sapiens | 20 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!