# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5120624 | B | Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-2 stimulation for 15 mins by FACS method | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA5120629 | T | Inhibition of JAK2 signaling pathway in human CHEP cells assessed as inhibition of EPO-induced cell survival preincubated for 1 hr followed by EPO addition and measured after 48 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA5120630 | B | Selectivity ratio of IC50 for inhibition of JAK2 signaling pathway in EPO-stimulated human CHEP cells to IC50 for inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation | Homo sapiens | 12 | assay format | Scientific Literature |