# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5152875 | B | Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysis | Homo sapiens | 13 | single protein format | Scientific Literature | ||
2. | ALA5152876 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in MDCK-MDR1 cells at 1 uM measured after 1 hrs by LC-MS/MS analysis | Canis lupus familiaris | 13 | cell-based format | Scientific Literature | ||
3. | ALA5152877 | P | 1-Octanol/aqueous buffer partition coefficient, logD of the compound at pH 7.4 by chromatographic method | 13 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA5152878 | P | Kinetic solubility of the compound in pH 6.8 JP2 fluid by precipitation method | 13 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA5152879 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM in the presence of NADPH regenerating system by LC/MS/MS analysis | Homo sapiens | 13 | microsome format | Scientific Literature | ||
6. | ALA5152880 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance at 1 uM in the presence of NADPH regenerating system by LC/MS/MS analysis | Mus musculus | 13 | microsome format | Scientific Literature |