# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5125637 | B | Binding affinity to recombinant Trypanosoma brucei rhodesiense rhodesain assessed as Kinact using Cbz-Phe-Arg-AMC as fluorogenic substrate measured for 10 mins every 30 seconds by fluorescence microplate reader assay | Trypanosoma brucei rhodesiense | 11 | single protein format | Scientific Literature | ||
2. | ALA5125638 | B | Binding affinity to recombinant Trypanosoma brucei rhodesiense rhodesain assessed as inhibition constant using Cbz-Phe-Arg-AMC as fluorogenic substrate measured for 10 mins every 30 seconds by fluorescence microplate reader assay | Trypanosoma brucei rhodesiense | 11 | single protein format | Scientific Literature | ||
3. | ALA5125639 | B | Binding affinity to recombinant Trypanosoma brucei rhodesiense rhodesain assessed as binding constant measured at second inhibition step using Cbz-Phe-Arg-AMC as fluorogenic substrate measured for 10 mins every 30 seconds by fluorescence microplate reader assay | Trypanosoma brucei rhodesiense | 11 | single protein format | Scientific Literature | ||
4. | ALA5125641 | F | Antitrypanosomal activity against Trypanosoma brucei brucei incubated for 24 hrs by ATPlite assay | Trypanosoma brucei brucei | 11 | organism-based format | Scientific Literature | ||
5. | ALA5125642 | B | Inhibition of Trypanosoma brucei rhodesiense rhodesain at 0.1 uM using Cbz-Phe-Arg-AMC as fluorogenic substrate measured for 10 mins every 30 seconds by fluorescence microplate reader assay | Trypanosoma brucei rhodesiense | 9 | single protein format | Scientific Literature | ||
6. | ALA5125643 | B | Inhibition of C-terminal His-tagged SARS-CoV-2 MPro expressed in Escherichia coli BL21(DE3) at 100 uM using Dabcyl-KTSAVLQSGFRKME-Edans as fluorogenic substrate incubated for 10 mins by FRET assay | Severe acute respiratory syndrome coronavirus 2 | 9 | assay format | Scientific Literature |