#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5163567	F	Surmountable antagonist activity at human V2 receptor expressed in CHO cells assessed as decrease in maximal response preincubated for 30 mins followed by vasopressin stimulation and measured after 30 mins	Homo sapiens	1	ALA5154831	cell-based format	Scientific Literature
2.	ALA5163568	F	Suppression of renal cyst development in embryonic kidney of 8-Br-cAMP induced C57BL/6 mouse mouse model of autosomal dominant polycystic kidney disease assessed as residence time dependent measured after 8 days	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
3.	ALA5163569	B	Displacement of conivaptan-red from SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition constant measured after 2 hrs by HTRF assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
4.	ALA5163570	B	Inhibition of conivaptan-red binding to SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as binding constant (Kon) measured after 2 hrs by HTRF competitive binding assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
5.	ALA5163571	B	Inhibition of conivaptan-red binding to SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as binding constant (Koff) measured after 2 hrs by HTRF competitive binding assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
6.	ALA5163572	B	Inhibition of conivaptan-red binding to SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells assessed as residence time (1/koff) measured after 2 hrs by HTRF competitive binding assay	Homo sapiens	10	ALA5154831	cell-based format	Scientific Literature
7.	ALA5163573	F	Antagonist activity at human V2 receptor expressed in CHO cells assessed as reduction in vasopressin induced cAMP production preincubated for 30 mins followed by vasopressin stimulation and measured after 30 mins	Homo sapiens	3	ALA5154831	cell-based format	Scientific Literature
8.	ALA5163575	F	Antagonist activity at human V2 receptor expressed in CHO cells assessed as recovery of cAMP production preincubated for 30 mins followed by compound washout and subsequent vasopressin stimulation for 30 mins and measured after 1 hr	Homo sapiens	3	ALA5154831	cell-based format	Scientific Literature
9.	ALA5163577	F	Antagonist activity at human V2 receptor expressed in CHO cells assessed as assessed as reversal target occupancy preincubated for 30 mins followed by vasopressin stimulation for 15 mins	Homo sapiens	1	ALA5154831	cell-based format	Scientific Literature
10.	ALA5163578	F	Suppression of renal cyst development in embryonic kidney of 8-Br-cAMP induced C57BL/6 mouse mouse model of autosomal dominant polycystic kidney disease measured after 8 days	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
11.	ALA5163579	F	Invivo antagonist activity at V2R in Pkd1 knockout mouse model of autosomal dominant polycystic kidney disease assessed as reduction in kidney size at 2 mg/kg, sc administered once daily treatment started from postnatal day 6 to 12 days	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
12.	ALA5163580	T	Toxicity in wild type mouse assessed as effect on kidney size	Mus musculus	10	ALA5154831	tissue-based format	Scientific Literature
13.	ALA5163581	T	Toxicity in wild type mouse assessed as effect on body weight	Mus musculus	10	ALA5154831	assay format	Scientific Literature
14.	ALA5163582	F	Invivo antagonist activity at V2R in Pkd1 knockout mouse model of autosomal dominant polycystic kidney disease assessed as reduction of renal cyst formation 2 mg/kg, sc administered once daily treatment started from postnatal day 6 to 12 days by hematoxylin and eosin staining based assay	Mus musculus	3	ALA5154831	organism-based format	Scientific Literature
15.	ALA5163583	A	Elimination rate constant in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
16.	ALA5163584	A	Half life in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
17.	ALA5163585	A	Tmax in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
18.	ALA5163586	A	Cmax in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
19.	ALA5163587	A	AUC (0 to t) in C57BL/6 mouse at 2 mg/kg, sc by LC-MS analysis	Mus musculus	10	ALA5154831	organism-based format	Scientific Literature
20.	ALA5163588	P	Equilibrium solubility of compound in water incubated for 24 hrs by UV-spectroscopy method		10	ALA5154831	small-molecule physicochemical format	Scientific Literature