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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5154145 B Inhibition of full length human PDE9A expressed in Sf9 insect cells using [3H]-cGMP as substrate incubated for 60 mins by microbeta scintillation counter analysis Homo sapiens 34 ALA5150071 cell-based format Scientific Literature 2. ALA5154146 B Selectivity index, ratio of IC50 for bovine brain PDE1 to IC50 for full length human PDE9A 16 ALA5150071 assay format Scientific Literature 3. ALA5154148 B Selectivity index, ratio of IC50 for full length human PDE2A to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 4. ALA5154149 B Selectivity index, ratio of IC50 for full length human PDE3B to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 5. ALA5154150 B Selectivity index, ratio of IC50 for human platelet PDE5A to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 6. ALA5154151 B Selectivity index, ratio of IC50 for full length human PDE7B to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 7. ALA5154152 B Selectivity index, ratio of IC50 for full length human PDE8A to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 8. ALA5154153 B Selectivity index, ratio of IC50 for full length human PDE10A to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 9. ALA5154154 B Selectivity index, ratio of IC50 for full length human PDE11A to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 10. ALA5154155 B Selectivity index, ratio of IC50 for full length human PDE4B to IC50 for full length human PDE9A Homo sapiens 4 ALA5150071 assay format Scientific Literature 11. ALA5154159 B Selectivity index, ratio of IC50 for bovine PDE6 to IC50 for full length human PDE9A 1 ALA5150071 assay format Scientific Literature 12. ALA5154160 A Blood clearance in Wistar rat at 1 mg/kg, po or 0.3 mg/kg, iv measured over 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5150071 organism-based format Scientific Literature 13. ALA5154161 A Volume of distribution at steady state in Wistar rat at 1 mg/kg, po or 0.3 mg/kg, iv measured over 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5150071 organism-based format Scientific Literature 14. ALA5154162 A MRT in Wistar rat at 0.3 mg/kg, iv measured over 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5150071 organism-based format Scientific Literature 15. ALA5154163 A Oral bioavailability in Wistar rat at 1 mg/kg measured over 24 hrs by LC-MS/MS analysis Rattus norvegicus 2 ALA5150071 organism-based format Scientific Literature 16. ALA5154164 A Blood clearance in dog at 1 mg/kg, po or 0.3 mg/kg, iv measured over 24 hrs by LC-MS/MS analysis Canis lupus familiaris 2 ALA5150071 organism-based format Scientific Literature 17. ALA5154165 A Volume of distribution at steady state in dog at 1 mg/kg, po or 0.3 mg/kg, iv measured over 24 hrs by LC-MS/MS analysis Canis lupus familiaris 2 ALA5150071 organism-based format Scientific Literature 18. ALA5154166 A MRT in dog at 0.3 mg/kg, iv measured over 24 hrs by LC-MS/MS analysis Canis lupus familiaris 2 ALA5150071 organism-based format Scientific Literature 19. ALA5154167 A Oral bioavailability in dog at 1 mg/kg measured over 24 hrs by LC-MS/MS analysis Canis lupus familiaris 2 ALA5150071 organism-based format Scientific Literature 20. ALA5154168 P Solubility of compound in PBS at pH 7 incubated for 24 hrs by UV based HPLC analysis 1 ALA5150071 small-molecule physicochemical format Scientific Literature