| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4650107 | B | Thermal Shift Assay. Domain start/stop: M626-G740 | Homo sapiens | 1,014 | single protein format | EUbOPEN Chemogenomic Library | ||
| 2. | ALA4725212 | T | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 3. | ALA4725213 | T | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 4. | ALA4725214 | T | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 5. | ALA5060015 | B | Thermal Shift Assay. Domain: start/stop: S229-K512 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 6. | ALA5060944 | B | Thermal Shift Assay. Domain: start/stop: N44-E168 | Homo sapiens | 1,502 | single protein format | EUbOPEN Chemogenomic Library | ||
| 7. | ALA5062802 | B | Thermal Shift Assay. Domain: start/stop: M1-L298 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 8. | ALA5063731 | B | Thermal Shift Assay. Domain: start/stop: M1-K294 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 9. | ALA5064660 | B | Thermal Shift Assay. Domain: start/stop: P449-E759 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 10. | ALA5065589 | B | Thermal Shift Assay. Domain: start/stop: M26-R383 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 11. | ALA5066518 | B | Thermal Shift Assay. Domain: start/stop: M1-S360 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 12. | ALA5067447 | B | Thermal Shift Assay. Domain: start/stop: E122-S403 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 13. | ALA5068376 | B | Thermal Shift Assay. Domain: start/stop: G861-E979 | Homo sapiens | 1,502 | single protein format | EUbOPEN Chemogenomic Library | ||
| 14. | ALA5111430 | F | Antiviral activity against MHV-nLuc infected in DBT cells assessed as effect on cell viability by LDH assay | Murine hepatitis virus | 15 | organism-based format | Scientific Literature | ||
| 15. | ALA5111431 | F | Antiviral activity against SARS-CoV-2 infected in human A549-ACE2 cells assessed as effect on cell viability pretreated with compound for 1 hr followed by viral infection measured after 2 hrs by Nano-Glo reagent based LDH assay | Severe acute respiratory syndrome coronavirus 2 | 5 | organism-based format | Scientific Literature | ||
| 16. | ALA5111457 | B | Inhibition of human wild type partial length PIKfyve (F1512 to C2098 residues) expressed in mammalian expression assessed as remaining activity at 1 uM by Kinomescan assay relative to control | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 17. | ALA5111458 | B | Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for 60 mins in presence of ATP by ADP-Glo assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 18. | ALA5111459 | B | Inhibition of PIKFYVE in HEK293 cells by NanoBRET assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 19. | ALA5111460 | B | Inhibition of wild-type human partial length MAST1 (S346 to V730 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA5111465 | F | Inhibition of His-6 tagged SARS-CoV-2 spike protein uptake in ACE2 overexpressing HEK293T cells at 1 uM incubated for 30 mins by DAPI staining based confocal microscopy analysis | Homo sapiens | 5 | cell-based format | Scientific Literature |
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