# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5131264 | T | Displacement of [3H]-HS665 from MOR in rat brain membranes | Rattus norvegicus | 15 | cell membrane format | Scientific Literature | ||
2. | ALA5131265 | T | Displacement of [3H]-HS665 from DOR in rat brain membranes | Rattus norvegicus | 15 | cell membrane format | Scientific Literature | ||
3. | ALA5131266 | B | Displacement of [3H]-HS665 from KOR in guinea pig brain membranes | Cavia porcellus | 15 | cell membrane format | Scientific Literature | ||
4. | ALA5131267 | F | Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation counting analysis relative to control | Cavia porcellus | 15 | cell membrane format | Scientific Literature | ||
5. | ALA5131268 | F | Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation counting analysis | Cavia porcellus | 15 | cell membrane format | Scientific Literature | ||
6. | ALA5131269 | F | Antinociceptive activity in CD-1 mouse assessed as maximum possible effect at 10 nmol, icv measured after 15 to 120 mins by tail-flick test | Mus musculus | 6 | organism-based format | Scientific Literature | ||
7. | ALA5131270 | F | Antinociceptive activity in CD-1 mouse assessed as maximum possible effect at 20 umol/kg, iv measured after 15 to 120 mins by tail-flick test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
8. | ALA5131271 | F | Antinociceptive activity in formalin-induced CD-1 mouse model of nociception assessed as reduction in total time spent in paw licking during early phase at 100 nmol, sc pretreated for 15 mins followed by formalin challenge measured up to 10 mins by formalin test | Mus musculus | 4 | organism-based format | Scientific Literature | ||
9. | ALA5131272 | F | Antinociceptive activity in formalin-induced CD-1 mouse model of nociception assessed as reduction in total time spent in paw licking during late phase at 100 nmol, sc pretreated for 15 mins followed by formalin challenge measured after 10 to 40 mins by formalin test | Mus musculus | 4 | organism-based format | Scientific Literature |