# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5117676 | Functional | Antiproliferative activity against human NCI-N87 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
2. | ALA5117678 | Functional | Antiproliferative activity against human HCT-116 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 18 | ALA5113481 | cell-based format | Scientific Literature | |
3. | ALA5117679 | Functional | Antiproliferative activity against human K562 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
4. | ALA5117680 | Functional | Antiproliferative activity against imatinib-resistant human K562 cells over expressing MDR1 after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
5. | ALA5117681 | Functional | Antiproliferative activity against human MIA PaCa-2 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
6. | ALA5117682 | Functional | Antiproliferative activity against human SK-OV-3 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
7. | ALA5117683 | Functional | Antiproliferative activity against human A549 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
8. | ALA5117684 | Functional | Antiproliferative activity against human MCF7 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
9. | ALA5117685 | Functional | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
10. | ALA5117686 | Functional | Antiproliferative activity against human HT-29 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 7 | ALA5113481 | cell-based format | Scientific Literature | |
11. | ALA5117687 | Functional | Cell cycle arrest in human HT-29 cells assessed as accumulation of cells in G2/M phase at 0.1 to 5 nM measured after 24 hrs by PI staining based flow cytometry method | Homo sapiens | 2 | ALA5113481 | cell-based format | Scientific Literature | |
12. | ALA5117688 | Functional | Cell cycle arrest in human HT-29 cells assessed as accumulation of cells in G2/M phase at 5 nM measured after 24 hrs by PI staining based flow cytometry method | Homo sapiens | 2 | ALA5113481 | cell-based format | Scientific Literature | |
13. | ALA5117689 | Functional | Induction of mitochondrial dysfunction in human HT-29 cells at 2 nM measured after 48 hrs by JC-1 staining based flow cytometry | Homo sapiens | 2 | ALA5113481 | cell-based format | Scientific Literature | |
14. | ALA5117690 | Binding | Inhibition of HDAC6 (unknown origin) measured by fluorometry assay | Homo sapiens | 8 | ALA5113481 | single protein format | Scientific Literature | |
15. | ALA5117691 | Binding | Inhibition of HDAC8 (unknown origin) measured by fluorometry assay | Homo sapiens | 8 | ALA5113481 | single protein format | Scientific Literature | |
16. | ALA5117692 | Binding | Inhibition of HDAC11 (unknown origin) measured by fluorometry assay | Homo sapiens | 8 | ALA5113481 | single protein format | Scientific Literature | |
17. | ALA5117699 | Physicochemical | Solubility of compound in water | 4 | ALA5113481 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA5117700 | ADME | Metabolic stability in rat liver microsomes assessed as half-life measured upto 6 hrs in presence of NADPH generating system by HPLC-MS/MS analysis | Rattus norvegicus | 5 | ALA5113481 | microsome format | Scientific Literature | |
19. | ALA5117701 | ADME | Metabolic stability in rat liver microsomes assessed as intrinsic clearance per mg protein measured upto 6 hrs in presence of NADPH generating system by HPLC-MS/MS analysis | Rattus norvegicus | 5 | ALA5113481 | microsome format | Scientific Literature | |
20. | ALA5117702 | ADME | Metabolic stability in human liver microsomes assessed as half-life measured upto 6 hrs in presence of NADPH generating system by HPLC-MS/MS analysis | Homo sapiens | 5 | ALA5113481 | microsome format | Scientific Literature |