# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5120720 | F | Antiviral activity against CHIKV S27 infected in human Huh-7 cells at MOI of 0.25 incubated for 2 days and measured by ATPLite assay | Chikungunya virus | 8 | ALA5113559 | organism-based format | Scientific Literature | |
2. | ALA5120721 | F | Antiviral activity against SINV AR339 infected in human Huh-7 cells measured by cytopathic effect inhibition assay | Sindbis virus | 8 | ALA5113559 | organism-based format | Scientific Literature | |
3. | ALA5120722 | F | Antiviral activity against HCV genotype 1b infected in human Huh7 cells incubated for 3 days and measured by luciferase reporter gene assay | Hepacivirus hominis | 8 | ALA5113559 | organism-based format | Scientific Literature | |
4. | ALA5120723 | F | Antiviral activity against DENV2 16681 infected in human Huh-7 cells assessed as reduction in viral replication at MOI of 1 to 5 incubated for 3 days | dengue virus type 2 | 8 | ALA5113559 | organism-based format | Scientific Literature | |
5. | ALA5120724 | T | Cytotoxicity against human Huh-7 cells measured after 2 days by ATPLite-based viability assay | Homo sapiens | 8 | ALA5113559 | cell-based format | Scientific Literature | |
6. | ALA5120725 | A | Cmax in male C57BL/6 mouse at 50 mg/kg, po measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
7. | ALA5120726 | A | Tmax in male C57BL/6 mouse at 50 mg/kg, po measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
8. | ALA5120727 | A | AUClast in male C57BL/6 mouse at 50 mg/kg, po measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
9. | ALA5120728 | A | Tlast in male C57BL/6 mouse at 50 mg/kg, po measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
10. | ALA5120729 | A | Cmax in male C57BL/6 mouse at 50 mg/kg, sc measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
11. | ALA5120730 | A | Tmax in male C57BL/6 mouse at 50 mg/kg, sc measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
12. | ALA5120731 | A | AUClast in male C57BL/6 mouse at 50 mg/kg, sc measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
13. | ALA5120732 | A | Tlast in male C57BL/6 mouse at 50 mg/kg, sc measured by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | organism-based format | Scientific Literature | |
14. | ALA5120733 | A | Stability of compound in fasted state simulated intestinal fluid incubated for 6 hrs and assessed as half-life at 1 uM by LC-MS/MS analysis | 1 | ALA5113559 | assay format | Scientific Literature | ||
15. | ALA5120734 | A | Stability of compound in simulated gastric fluid incubated for 6 hrs and assessed as half-life at 1 uM by LC-MS/MS analysis | 1 | ALA5113559 | assay format | Scientific Literature | ||
16. | ALA5120735 | A | Stability of compound in mouse plasma assessed as half-life incubated for 24 hrs and assessed as half-life at 1 uM by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | cell-free format | Scientific Literature | |
17. | ALA5120736 | A | Stability of compound in human plasma assessed as half-life incubated for 24 hrs and assessed as half-life at 1 uM by LC-MS/MS analysis | Homo sapiens | 1 | ALA5113559 | cell-free format | Scientific Literature | |
18. | ALA5120737 | A | Metabolic stability in mouse liver microsomes preincubated for 5 mins followed by addition of NADPH and assessed as intrinsic clearance by LC-MS/MS analysis | Mus musculus | 1 | ALA5113559 | microsome format | Scientific Literature | |
19. | ALA5120738 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance preincubated for 5 mins followed by addition of NADPH and assessed as intrinsic clearance by LC-MS/MS analysis | Homo sapiens | 1 | ALA5113559 | microsome format | Scientific Literature | |
20. | ALA5120739 | A | Stability of compound in simulated gastric fluid incubated for 6 hrs at 1 uM and assessed as compound remaining after 6 hrs by LC-MS/MS analysis | 1 | ALA5113559 | assay format | Scientific Literature |