# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5148357 | B | Agonist activity against human LXRalpha expressed in human HEK293T cells co-expressing CMX-GAL4N-hLXRalpha incubated for 24 hrs by reporter gene assay | Homo sapiens | 19 | ALA5143705 | cell-based format | Scientific Literature | |
2. | ALA5148358 | B | Agonist activity against human LXRbeta expressed in human HEK293T cells co-expressing CMX-GAL4N-hLXRbeta incubated for 24 hrs by reporter gene assay | Homo sapiens | 19 | ALA5143705 | cell-based format | Scientific Literature | |
3. | ALA5148359 | B | Selectivity index, ratio of EC50 for agonist activity at human LXRalpha to EC50 for agonist activity at LXRbeta | Homo sapiens | 19 | ALA5143705 | assay format | Scientific Literature | |
4. | ALA5148360 | T | Toxicity in human HEK293 cells assessed as reduction in cell viability at 10 uM | Homo sapiens | 19 | ALA5143705 | cell-based format | Scientific Literature | |
5. | ALA5148361 | B | Partial agonist activity against human LXRalpha in human HEK293T cells incubated for 24 hrs by reporter gene assay relative to T0901317 | Homo sapiens | 1 | ALA5143705 | cell-based format | Scientific Literature | |
6. | ALA5148362 | B | Partial agonist activity against human LXRbeta in human HEK293T cells incubated for 24 hrs by reporter gene assay T0901317 | Homo sapiens | 1 | ALA5143705 | cell-based format | Scientific Literature |