# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5131046 | B | Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in LDH release pretreated for 0.5 hrs followed by stimulation with nigericin for 1 hr by LDH release assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
2. | ALA5131047 | B | Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hrs followed by stimulation with nigericin for 1 hr by ELISA | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA5131048 | B | Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hrs followed by stimulation with nigericin for 1 hr by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA5131049 | B | Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in caspase-1 level pretreated for 0.5 hrs followed by stimulation with nigericin for 1 hr by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA5131050 | B | Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in pyroptosis at 20 uM pretreated for 0.5 hrs followed by stimulation with nigericin for 1 hr by fluorescent microscopic analysis | Mus musculus | 1 | cell-based format | Scientific Literature |