| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4650107 | B | Thermal Shift Assay. Domain start/stop: M626-G740 | Homo sapiens | 1,014 | single protein format | EUbOPEN Chemogenomic Library | ||
| 2. | ALA4725212 | T | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 3. | ALA4725213 | T | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 4. | ALA4725214 | T | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 5. | ALA5060015 | B | Thermal Shift Assay. Domain: start/stop: S229-K512 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 6. | ALA5060944 | B | Thermal Shift Assay. Domain: start/stop: N44-E168 | Homo sapiens | 1,502 | single protein format | EUbOPEN Chemogenomic Library | ||
| 7. | ALA5062802 | B | Thermal Shift Assay. Domain: start/stop: M1-L298 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 8. | ALA5063731 | B | Thermal Shift Assay. Domain: start/stop: M1-K294 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 9. | ALA5064660 | B | Thermal Shift Assay. Domain: start/stop: P449-E759 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 10. | ALA5065589 | B | Thermal Shift Assay. Domain: start/stop: M26-R383 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 11. | ALA5066518 | B | Thermal Shift Assay. Domain: start/stop: M1-S360 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 12. | ALA5067447 | B | Thermal Shift Assay. Domain: start/stop: E122-S403 | Homo sapiens | 1,499 | single protein format | EUbOPEN Chemogenomic Library | ||
| 13. | ALA5068376 | B | Thermal Shift Assay. Domain: start/stop: G861-E979 | Homo sapiens | 1,502 | single protein format | EUbOPEN Chemogenomic Library | ||
| 14. | ALA5141671 | B | Binding affinity to N-terminal GST-tagged human NSD2 PWWP1 domain (208 to 369 residues) expressed in Escherichia coli BL2I (DE3) cells assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA5141681 | B | Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in human KMS-11 cells assessed as induction of NSD2 degradation 2.5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA5141682 | B | Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in human NCI-H929 cells assessed as induction of NSD2 degradation 2.5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA5141685 | B | Protac activity at CRBN/IKZF1 in human KMS-11 cells assessed as induction of IKZF1 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA5141686 | B | Protac activity at CRBN/IKZF1 in human NCI-H929 cells assessed as induction of IKZF1 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA5141687 | B | Protac activity at CRBN/IKZF3 in human KMS-11 cells assessed as induction of IKZF3 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 20. | ALA5141688 | B | Protac activity at CRBN/IKZF3 in human NCI-H929 cells assessed as induction of IKZF3 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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