| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5098671 | B | Inhibition of CDK9 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of ATP at Km concentration by plate reader analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 2. | ALA5098672 | B | Inhibition of CDK1 (unknown origin) using 5FAM-RRRFRPASPLRGPPK-COOH as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of ATP at Km concentration by plate reader analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 3. | ALA5098673 | B | Inhibition of CDK2 (unknown origin) using FL-Ahx-QSPKKG-CONH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of ATP at Km concentration by plate reader analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 4. | ALA5098674 | B | Inhibition of CDK9 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of 5 mM ATP by plate reader analysis | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 5. | ALA5098677 | P | Lipophilicity, logD of the compound in octanol/buffer at pH 7.4 by shake flask method | 38 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA5098678 | P | Solubility of the compound in phosphate buffer at pH 7.4 | 37 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA5098697 | B | Selectivity index, ratio of IC50 for inhibition of CDK1 (unknown origin) using 5FAM-RRRFRPASPLRGPPK-COOH as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of ATP at Km concentration to IC50 for inhibition of CDK9 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of ATP at Km concentration | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA5098698 | B | Selectivity index, ratio of IC50 for inhibition of CDK2 (unknown origin) using FL-Ahx-QSPKKG-CONH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of ATP at Km concentration to IC50 for inhibition of CDK9 (unknown origin) using FITC-X-GSRTPMY-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured after 90 mins in the presence of ATP at Km concentration | Homo sapiens | 1 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!