#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5121790	Toxicity	Cytotoxicity against mouse NIH/3T3 cells overexpressing FGFR3 S249C assessed as cell growth inhibition incubated for 5 days by CellTitre-Glo assay	Mus musculus	14	ALA5120772	cell-based format	Scientific Literature
2.	ALA5121791	ADME	Intrinsic clearance in human liver microsomes	Homo sapiens	15	ALA5120772	microsome format	Scientific Literature
3.	ALA5121792	Toxicity	Inhibition of hERG channel expressed in CHO cells at -80 mV holding potential by Qpatch clamp method	Homo sapiens	13	ALA5120772	cell-based format	Scientific Literature
4.	ALA5121793	Physicochemical	Lipophilicity, logD of the compound in 1-octanol and phosphate buffer at pH 7.4 by LC-MS analysis		14	ALA5120772	small-molecule physicochemical format	Scientific Literature
5.	ALA5121794	ADME	Permeability of the compound in aqueous buffer at pH 6.5 incubated for 2 hrs by PAMPA based HPLC analysis		14	ALA5120772	assay format	Scientific Literature
6.	ALA5121795	ADME	Plasma concentration in ICR mouse at 30 mg/kg, po measured after 6 hrs of administration by LC-MS/MS analysis	Mus musculus	4	ALA5120772	organism-based format	Scientific Literature
7.	ALA5121796	Functional	Invivo inhibition of FGFR3 phosphorylation in human NIH/3T3 cells overexpressing FGFR3 S249C xenografted in Balb/c nude mouse at 30 mg/kg, po administered as single dose and measured after 6 hrs by sandwich ELISA analysis relative to control	Mus musculus	4	ALA5120772	organism-based format	Scientific Literature
8.	ALA5121856	Binding	Inhibition of wild type N-terminal GST tagged FGFR3 (436 to 806 residues) (unknown origin) expressed in sf21 insect cells preincubated for 30 mins followed by substrate addition and measured after 30 mins in presence of ATP by off-chip mobility shift assay	Homo sapiens	14	ALA5120772	cell-based format	Scientific Literature