# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5100500 | B | Inhibition of human TASK-1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 8 | ALA5096243 | cell-based format | Scientific Literature | |
2. | ALA5100502 | B | Inhibition of human TASK-3 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 2 | ALA5096243 | cell-based format | Scientific Literature | |
3. | ALA5100503 | B | Inhibition of human TASK-1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 6 | ALA5096243 | cell-based format | Scientific Literature | |
4. | ALA5100504 | B | Inhibition of human TASK-3 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 4 | ALA5096243 | cell-based format | Scientific Literature | |
5. | ALA5100505 | B | Inhibition of human TASK-4 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
6. | ALA5100506 | B | Inhibition of rat THIK-1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Rattus norvegicus | 1 | ALA5096243 | cell-based format | Scientific Literature | |
7. | ALA5100507 | B | Inhibition of human TRAAK expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
8. | ALA5100508 | B | Inhibition of human TREK-1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
9. | ALA5100509 | B | Inhibition of human TREK-2 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
10. | ALA5100510 | B | Inhibition of mouse TRESK expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Mus musculus | 1 | ALA5096243 | cell-based format | Scientific Literature | |
11. | ALA5100511 | B | Inhibition of human Kv1.5 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
12. | ALA5100512 | B | Inhibition of human Kv2.1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
13. | ALA5100513 | B | Inhibition of human Kv4.3 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
14. | ALA5100514 | B | Inhibition of human Kir2.1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
15. | ALA5100515 | B | Inhibition of human ERG expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
16. | ALA5100516 | B | Inhibition of human BK potassium channel expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
17. | ALA5100517 | F | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation at 10 uM incubated for 4 days by MTT assay | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
18. | ALA5100518 | F | Antiproliferative activity against human MCF7 cells with wild type TASK-1 expressing GFP induced by shGFP assessed as inhibition of cell proliferation at 0.148 uM incubated for 24 to 72 hrs by trypan blue exclusion method | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
19. | ALA5100519 | F | Antiproliferative activity against human MCF7 cells with shAP3 induced TASK-1 knockdown assessed as inhibition of cell proliferation at 0.148 uM incubated for 24 to 72 hrs by trypan blue exclusion method | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature | |
20. | ALA5100520 | F | Antiproliferative activity against human MCF7 cells with shBP3 induced TASK-1 knockdown assessed as inhibition of cell proliferation at 0.148 uM incubated for 24 to 72 hrs by trypan blue exclusion method | Homo sapiens | 1 | ALA5096243 | cell-based format | Scientific Literature |