| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5142534 | B | Inhibition of ARC-1063 fluorescent probe binding to recombinant human PKAC-alpha incubated for 1 hr by time-gated luminescence intensity based displacement assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 2. | ALA5142535 | B | Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as dissociation equilibrium constant preincubated for 1 hr followed by photoluminescent probe addition by time-gated luminescence intensity based assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA5142536 | B | Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as dissociation half life preincubated for 1 hr followed by photoluminescent probe addition by time-gated luminescence intensity based assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 4. | ALA5142537 | B | Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as dissociation rate constant (koff) preincubated for 1 hr followed by photoluminescent probe addition by time-gated luminescence intensity based assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA5142538 | B | Displacement of ARC-1063 fluorescent probe from recombinant human PKAC-alpha assessed as binding constant (kon) preincubated for 1 hr followed by photoluminescent probe addition by time-gated luminescence intensity based assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA5142539 | B | Inhibition of recombinant human PKAC-alpha assessed as residual activity at 0.1 uM in presence of ATP by radiometric filter-binding assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA5142540 | B | Inhibition of recombinant human GST-tagged ROCK-2 catalytic domain (1 to 552 residues) assessed as residual activity at 0.1 uM in presence of ATP by radiometric filter-binding assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA5142541 | B | Inhibition of human PKBalpha assessed as residual activity at 0.1 uM in presence of ATP by radiometric filter-binding assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA5142542 | B | Inhibition of human PKB-beta assessed as residual activity at 0.1 uM in presence of ATP by radiometric filter-binding assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA5142571 | B | Inhibition of N-terminal 6His-tagged recombinant human spiked MSK1 (2 to end residues) assessed as residual activity relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA5142572 | B | Selectivity index, ratio of Kd for N-terminal 6His-tagged active recombinant human spiked Akt3 S472D mutant (117 to end residues) to Kd for human recombinant PKACalpha | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA5142573 | B | Inhibition of N-terminal 6His-tagged active recombinant full length human Aurora A-mediated phosphorylation assessed as residual activity at 100 nM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5142574 | B | Inhibition of N-terminal 6His-tagged active recombinant full length human Aurora B-mediated phosphorylation assessed as residual activity at 100 nM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
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