| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5147883 | B | Binding affinity to recombinant His-tagged full length human PDI-b' x domain substrate binding pocket expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in fluorescence intensity at 100 uM incubated for 10 mins by tryptophan fluorescence based assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA5147884 | B | Binding affinity to recombinant His-tagged full length human PDI-b' x domain substrate binding pocket expressed in Escherichia coli BL21 (DE3) cells assessed as inhibition constant at 100 uM incubated for 10 mins by tryptophan fluorescence based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA5147885 | B | Inhibition of recombinant His-tagged full length human PDI reductase activity assessed as inhibition of PDI/DTT-mediated cleavage of disulfide bond in insulin at 100 uM incubated for 40 mins by spectrophotometric analysis | Homo sapiens | 3 | single protein format | Scientific Literature |
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