| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5100323 | B | Inhibition of N-terminal His-Avi tagged recombinant human FGFR3 (447 to 761 residues) expressed in an Sf9 infected baculovirus expression system using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition and measured after 1 hr by HTRF assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 2. | ALA5100325 | B | Inhibition of recombinant human FGFR1 using biotin-EQEDEPEGDYFEWLE-amide as substrate preincubated for 5 to 10 mins followed by substrate addition and measured after 1 hr by HTRF assay | Homo sapiens | 29 | single protein format | Scientific Literature | ||
| 3. | ALA5100327 | B | Inhibition of TEL-FGFR3 in mouse BaF3 cells incubated for 125 mins by plate reader analysis | Mus musculus | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA5100328 | B | Inhibition of wild type partial length human FLT3 (V592 to Y969 residues) expressed in bacterial expression system using Ulight-p70S6K peptide substrate incubated for 90 mins in presence of ATP by HTRF assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 5. | ALA5100329 | B | Inhibition of wild type partial length human TRKA (G475 to G790 residues) expressed in mammalian expression system using Ulight-p70S6K peptide substrate incubated for 90 mins in presence of ATP by HTRF assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 6. | ALA5100330 | B | Inhibition of wild type partial length human KIT (I571 to D952 residues) expressed in bacterial expression system using Ulight-p70S6K peptide substrate incubated for 90 mins in presence of ATP by HTRF assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 7. | ALA5100331 | B | Inhibition of wild type partial length human PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system using Ulight-p70S6K peptide substrate incubated for 90 mins in presence of ATP by HTRF assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 8. | ALA5100344 | B | Selectivity ratio of IC50 for recombinant human FGFR1 to IC50 for recombinant human FGFR3 | Homo sapiens | 8 | assay format | Scientific Literature |
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