# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5166518 | Binding | Inhibition of Staphylococcus aureus ATTC 25923 DNA gyrase | Staphylococcus aureus | 7 | ALA5154899 | protein complex format | Scientific Literature | |
2. | ALA5166519 | Physicochemical | Kinetic solubility of compound at 200 uM incubated for 20 hrs by shake flask method based HPLC-DAD analysis | 42 | ALA5154899 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA5166520 | Physicochemical | n-Octanol/phosphate buffer partition coefficient, logD of the compound at pH 7.4 incubated for 3 hrs by shake flask method based HPLC-DAD analysis | 40 | ALA5154899 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5166521 | Toxicity | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 40 | ALA5154899 | cell-based format | Scientific Literature | |
5. | ALA5166522 | Binding | Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase | Mycobacterium tuberculosis | 11 | ALA5154899 | protein complex format | Scientific Literature | |
6. | ALA5166523 | Functional | Antibacterial activity against Mycobacterium tuberculosis H37Rv assessed as inhibition of bacterial growth measured after 8 days by Alamar blue reagent based broth microdilution method | Mycobacterium tuberculosis | 42 | ALA5154899 | organism-based format | Scientific Literature | |
7. | ALA5166524 | Functional | Antibacterial activity against Staphylococcus aureus ATTC 25923 assessed as inhibition of bacterial growth measured after 8 days by Alamar blue reagent based broth microdilution method | Staphylococcus aureus | 42 | ALA5154899 | organism-based format | Scientific Literature | |
8. | ALA5166525 | Functional | Antibacterial activity against Escherichia coli ATTC 25922 assessed as inhibition of bacterial growth measured after 8 days by Alamar blue reagent based broth microdilution method | Escherichia coli | 42 | ALA5154899 | organism-based format | Scientific Literature | |
9. | ALA5166526 | Functional | Antibacterial activity against wild type Mycobacterium tuberculosis H37Rv assessed as inhibition of bacterial growth incubated for 11 days | Mycobacterium tuberculosis | 7 | ALA5154899 | organism-based format | Scientific Literature | |
10. | ALA5166527 | Functional | Antibacterial activity against Mycobacterium tuberculosis H37Rv gyrA -FDASTetON-1 hypomorph assessed as inhibition of bacterial growth incubated for 11 days | Mycobacterium tuberculosis | 7 | ALA5154899 | organism-based format | Scientific Literature | |
11. | ALA5166528 | Functional | Selectivity ratio of MIC50 for wild type Mycobacterium tuberculosis H37Rv to MIC50 for Mycobacterium tuberculosis H37Rv gyrA -FDASTetON-1 hypomorph | 7 | ALA5154899 | assay format | Scientific Literature | ||
12. | ALA5166529 | Functional | Selectivity ratio of MIC99 for wild type Mycobacterium tuberculosis H37Rv to MIC99 for Mycobacterium tuberculosis H37Rv gyrA -FDASTetON-1 hypomorph | 7 | ALA5154899 | assay format | Scientific Literature |