| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5129797 | ADME | Drug metabolism in human plasma assessed as metabolite formation at 10 uM measured after 0 to 60 mins by HPLC based LC/MS-MS analysis | Homo sapiens | 5 | ALA5126603 | cell-free format | Scientific Literature | |
| 2. | ALA5129800 | Binding | Displacement of 125I-cyanopindolol from human beta2 adrenoceptor expressed in CHO-K1 cell membrane measured after 1 hr by Cheng-prusoff equation analysis | Homo sapiens | 10 | ALA5126603 | cell membrane format | Scientific Literature | |
| 3. | ALA5129817 | ADME | Drug metabolism in rat hepatocytes assessed as metabolite formation at 10 uM measured after 0 to 60 mins by HPLC based LC/MS-MS analysis | Rattus norvegicus | 5 | ALA5126603 | cell-based format | Scientific Literature | |
| 4. | ALA5129818 | ADME | Drug metabolism in human hepatocytes assessed as metabolite formation at 10 uM measured after 0 to 60 mins by HPLC based LC/MS-MS analysis | Homo sapiens | 5 | ALA5126603 | cell-based format | Scientific Literature | |
| 5. | ALA5129819 | ADME | Drug metabolism in rat plasma assessed as metabolite formation at 10 uM measured after 0 to 60 mins by HPLC based LC/MS-MS analysis | Rattus norvegicus | 5 | ALA5126603 | cell-free format | Scientific Literature | |
| 6. | ALA5129820 | ADME | Cmax in Dunkin-Hartley guinea pig lung at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | tissue-based format | Scientific Literature | |
| 7. | ALA5129821 | ADME | Tmax in Dunkin-Hartley guinea pig lung at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | tissue-based format | Scientific Literature | |
| 8. | ALA5129822 | ADME | AUClast in Dunkin-Hartley guinea pig lung at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | tissue-based format | Scientific Literature | |
| 9. | ALA5129823 | ADME | AUCinfinity in Dunkin-Hartley guinea pig lung at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | tissue-based format | Scientific Literature | |
| 10. | ALA5129824 | ADME | Half life in Dunkin-Hartley guinea pig lung at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | tissue-based format | Scientific Literature | |
| 11. | ALA5129825 | ADME | Cmax in Dunkin-Hartley guinea pig plasma at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | cell-free format | Scientific Literature | |
| 12. | ALA5129826 | ADME | Tmax in Dunkin-Hartley guinea pig plasma at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | cell-free format | Scientific Literature | |
| 13. | ALA5129827 | ADME | AUClast in Dunkin-Hartley guinea pig plasma at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | cell-free format | Scientific Literature | |
| 14. | ALA5129828 | ADME | AUCinfinity in Dunkin-Hartley guinea pig plasma at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | cell-free format | Scientific Literature | |
| 15. | ALA5129829 | ADME | Half life in Dunkin-Hartley guinea pig plasma at 500 nmol/Kg, IT(Intratracheal) measured after 72 hrs by LC/MS-MS analysis | Cavia porcellus | 3 | ALA5126603 | cell-free format | Scientific Literature | |
| 16. | ALA5129830 | Toxicity | Inhibition of human ERG by patch clamp method | Homo sapiens | 3 | ALA5126603 | assay format | Scientific Literature | |
| 17. | ALA5129831 | Binding | Inhibition of human NaV1.5 channel | Homo sapiens | 3 | ALA5126603 | single protein format | Scientific Literature | |
| 18. | ALA5129832 | Binding | Inhibition of human CaV1.2 channel | Homo sapiens | 3 | ALA5126603 | single protein format | Scientific Literature | |
| 19. | ALA5129833 | Toxicity | Mutagenicity in Salmonella typhimurium assessed as induction of reverse mutation by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | ALA5126603 | assay format | Scientific Literature | |
| 20. | ALA5129834 | Toxicity | Mutagenicity in Escherichia coli assessed as induction of reverse mutation by Ames test | Escherichia coli | 3 | ALA5126603 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!