# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5167945 | F | Cytotoxicity against human SH-SY5Y cells expressing low level of topoisomerase I/II measured after 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
2. | ALA5167946 | F | Cytotoxicity against human MDA-MB-231 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
3. | ALA5167947 | F | Cytotoxicity against human HCT-116 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
4. | ALA5167948 | F | Cytotoxicity against human MCF7 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
5. | ALA5167949 | F | Cytotoxicity against human A-375 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
6. | ALA5167950 | F | Cytotoxicity against human A549 cells expressing high level of topoisomerase I/II measured after 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
7. | ALA5167951 | T | Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
8. | ALA5167952 | T | Cytotoxicity against human HEK293T cells measured after 72 hrs by MTT assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
9. | ALA5167955 | B | Inhibition of DNA topoisomerase I (unknown origin) relaxation activity at 100 uM incubated for 30 mins by chemiDoc system | Homo sapiens | 7 | single protein format | Scientific Literature | ||
10. | ALA5167956 | B | Inhibition of DNA topoisomerase I (unknown origin) relaxation activity at 50 uM incubated for 30 mins by chemiDoc system | Homo sapiens | 2 | single protein format | Scientific Literature | ||
11. | ALA5167957 | B | Inhibition of human DNA topoisomerase II-alpha relaxation activity at 100 uM incubated for 30 mins by chemiDoc system | Homo sapiens | 2 | single protein format | Scientific Literature | ||
12. | ALA5167959 | B | Poison activity at human topoisomerase II-alpha assessed as stabilization of enzyme-DNA cleavage complex by measuring nicked DNA formation at 100 uM after 60 mins by agarose gel electrophoresis method | Homo sapiens | 3 | single protein format | Scientific Literature |