| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5130382 | B | Binding affinity to human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 incubated for 1 hr by time-resolved fluorescence assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 2. | ALA5130383 | F | Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as reduction in cAMP accumulation incubated for 2 hrs under dark condition by LANCE cAMP assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 3. | ALA5130384 | F | Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as stimulation intracellular calcium mobilization measured after 180 secs by Fluo-3-AM dye based fluorescence assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 4. | ALA5130385 | F | Agonist activity at human GLP-1R assessed as increase in ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 20 mins by AlphaLISA assay | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 5. | ALA5130386 | F | Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as increase in beta arrestin-2 recruitment incubated for 1 hr by chemiluminescence based pathHunter assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 6. | ALA5130388 | F | Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as reduction in cAMP accumulation by measuring maximum efficacy incubated for 2 hrs under dark condition by LANCE cAMP assay relative to GLP1 | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 7. | ALA5130389 | F | Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as stimulation intracellular calcium mobilization by measuring maximum efficacy measured after 180 secs by Fluo-3-AM dye based fluorescence assay relative to GLP1 | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 8. | ALA5130390 | F | Agonist activity at human GLP-1R assessed as increase in ERK1/2 phosphorylation by measuring maximum efficacy at Thr202/Tyr204 residues incubated for 20 mins by AlphaLISA assay relative to GLP1 | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 9. | ALA5130391 | F | Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as increase in beta arrestin-2 recruitment by measuring maximum efficacy incubated for 1 hr by chemiluminescence based pathHunter assay relative to GLP1 | Homo sapiens | 21 | cell-based format | Scientific Literature |
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