| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5145222 | Functional | Agonist activity at human GPR38 expressed in COS-7 cells | Homo sapiens | 22 | ALA5143563 | cell-based format | Scientific Literature | |
| 2. | ALA5145224 | Binding | Agonist activity at rabbit GPR38 expressed in COS-7 cells | Oryctolagus cuniculus | 22 | ALA5143563 | cell-based format | Scientific Literature | |
| 3. | ALA5145225 | ADME | Inhibition of CYP3A4 in human liver microsomes assessed as remaining activity | Homo sapiens | 17 | ALA5143563 | microsome format | Scientific Literature | |
| 4. | ALA5145226 | Physicochemical | Lipophilicity, logD of the compound at pH 7.4 | 12 | ALA5143563 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA5145227 | Binding | Ex vivo agonist activity at GPR38 in rabbit duodenum muscle tissue assessed as intestinal contractile activity | Oryctolagus cuniculus | 5 | ALA5143563 | tissue-based format | Scientific Literature | |
| 6. | ALA5145228 | Binding | Potency index, ratio of GSK962040 EC50 to test compound EC50 for Ex vivo agonist activity at GPR38 in rabbit duodenum muscle tissue | Oryctolagus cuniculus | 1 | ALA5143563 | tissue-based format | Scientific Literature | |
| 7. | ALA5145229 | ADME | Effective permeability of the compound at pH 5 by PAMPA assay | 1 | ALA5143563 | assay format | Scientific Literature | ||
| 8. | ALA5145230 | ADME | Effective permeability of the compound at pH 7.4 by PAMPA assay | 1 | ALA5143563 | assay format | Scientific Literature | ||
| 9. | ALA5145231 | ADME | Protein binding in human | Homo sapiens | 1 | ALA5143563 | assay format | Scientific Literature | |
| 10. | ALA5145232 | ADME | Protein binding in rabbit | Oryctolagus cuniculus | 1 | ALA5143563 | assay format | Scientific Literature | |
| 11. | ALA5145233 | ADME | Inhibition of CYP1A2 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA5143563 | single protein format | Scientific Literature | |
| 12. | ALA5145234 | ADME | Inhibition of CYP2C9 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA5143563 | single protein format | Scientific Literature | |
| 13. | ALA5145235 | ADME | Inhibition of CYP2D6 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA5143563 | single protein format | Scientific Literature | |
| 14. | ALA5145236 | ADME | Inhibition of CYP3A4 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA5143563 | single protein format | Scientific Literature |
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