| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5145638 | B | Inhibition of TRPC5 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 2. | ALA5145639 | B | Inhibition of human TRPC3 channel expressed in HEK293 cells assessed as inhibition of OAG-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5145640 | B | Inhibition of TRPC4 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5145641 | B | Inhibition of TRPC6 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of OAG-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5145642 | B | Inhibition of TRPC7 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of GSK1702934A-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5145643 | B | Inhibition of human TRPC5 channel expressed in HEK293 cells assessed as inhibition of EA-evoked channel current measured at +80 mV by whole-cell voltage clamp assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA5145644 | T | Cytotoxicity against primary mouse hepatocytes assessed as reduction in cell viability at 1 to 10 uM by MTT assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA5145645 | T | Cytotoxicity against mouse MPC5 cells assessed as reduction in cell viability at 1 to 10 uM by MTT assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA5145646 | F | Reno-protectant activity against protamine sulfate-induced podocytes injury in mouse MPC5 cells assessed as reduction in PS-induced podocytes rearrangement and rupture of stress fibers at 0.1 to 3 uM pretreated for 30 mins followed by stimulation with PS for 100 mins | Mus musculus | 2 | cell-based format | Scientific Literature |
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