#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5135988	A	Oral bioavailability in mouse blood at 15 mg/kg	Mus musculus	1	ALA5131534	organism-based format	Scientific Literature
2.	ALA5135989	A	Volume of distribution at steady state in mouse blood at 5 mg/kg, iv	Mus musculus	1	ALA5131534	organism-based format	Scientific Literature
3.	ALA5135990	B	Antagonist activity at gardiquimod stimulated human TRL7 overexpressed in HEK293 cells assessed as inhibition of NF kappa B/Ap-1 activation preincubated with compound for 30 mins followed by gardiquimod stimulation measured after 22 hrs by SEAP reporter assay	Homo sapiens	34	ALA5131534	cell-based format	Scientific Literature
4.	ALA5135991	B	Antagonist activity at R848 stimulated human TRL8 overexpressed in HEK293 cells assessed as inhibition of NF kappa B/Ap-1 activation preincubated with compound for 30 mins followed by R848 stimulation measured after 22 hrs by SEAP reporter assay	Homo sapiens	33	ALA5131534	cell-based format	Scientific Literature
5.	ALA5135992	B	Antagonist activity at ODN2006 stimulated human TRL9 overexpressed in HEK293 cells assessed as inhibition of NF kappa B/Ap-1 activation preincubated with compound for 30 mins followed by ODN2006 stimulation measured after 22 hrs by SEAP reporter assay	Homo sapiens	10	ALA5131534	cell-based format	Scientific Literature
6.	ALA5135993	B	Selectivity ratio of IC50 for human TLR9 to IC50 for human TLR7	Homo sapiens	25	ALA5131534	assay format	Scientific Literature
7.	ALA5135994	B	Antagonist activity at Poly C stimulated human TRL3 overexpressed in HEK293 cells assessed as inhibition of NF kappa B/Ap-1 activation preincubated with compound for 30 mins followed by Poly C stimulation measured after 22 hrs by SEAP reporter assay	Homo sapiens	1	ALA5131534	cell-based format	Scientific Literature
8.	ALA5135995	B	Antagonist activity at LPD-RK stimulated human TRL4 overexpressed in HEK293 cells assessed as inhibition of NF kappa B/Ap-1 activation preincubated with compound for 30 mins followed by LPD-RK stimulation measured after 22 hrs by SEAP reporter assay	Homo sapiens	1	ALA5131534	cell-based format	Scientific Literature
9.	ALA5135996	B	Antagonist activity at ODN-2216 stimulated TLR9 in human PBMC cells assessed as inhibition of IL-6 production by ELISA analysis	Homo sapiens	1	ALA5131534	cell-based format	Scientific Literature
10.	ALA5135997	B	Antagonist activity at gardiquimod stimulated TRL7 in human PBMC cells assessed as inhibition of IL-6 production by ELISA analysis	Homo sapiens	1	ALA5131534	cell-based format	Scientific Literature
11.	ALA5135998	B	Antagonist activity at ODN-2216 stimulated TLR9 in human whole blood assessed as inhibition of IL-6 production by ELISA analysis	Homo sapiens	1	ALA5131534	tissue-based format	Scientific Literature
12.	ALA5135999	B	Antagonist activity at R848 stimulated TRL8 in human whole blood assessed as inhibition of IL-6 production by ELISA analysis	Homo sapiens	1	ALA5131534	tissue-based format	Scientific Literature
13.	ALA5136000	B	Antagonist activity at gardiquimod stimulated TRL7 in human whole blood assessed as inhibition of IL-6 production by ELISA analysis	Homo sapiens	1	ALA5131534	tissue-based format	Scientific Literature
14.	ALA5136001	B	Antagonist activity at ODN-2216 stimulated TLR9 in mouse whole blood assessed as inhibition of IL-6 production by ELISA analysis	Mus musculus	1	ALA5131534	tissue-based format	Scientific Literature
15.	ALA5136002	B	Antagonist activity at gardiquimod stimulated TRL7 in mouse whole blood assessed as inhibition of IL-6 production by ELISA analysis	Mus musculus	1	ALA5131534	tissue-based format	Scientific Literature
16.	ALA5136003	A	Plasma protein binding in human assessed as free fraction	Homo sapiens	1	ALA5131534	cell-free format	Scientific Literature
17.	ALA5136004	A	Plasma protein binding in rat assessed as free fraction	Rattus norvegicus	1	ALA5131534	cell-free format	Scientific Literature
18.	ALA5136005	A	Plasma protein binding in mouse assessed as free fraction	Mus musculus	1	ALA5131534	cell-free format	Scientific Literature
19.	ALA5136006	A	Tmax in mouse blood at 15 mg/kg, po	Mus musculus	1	ALA5131534	organism-based format	Scientific Literature
20.	ALA5136007	A	Cmax in mouse blood at 15 mg/kg, po	Mus musculus	1	ALA5131534	organism-based format	Scientific Literature