# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5166382 | B | Inhibition of recombinant full length human DAO preincubated with compound for 20 mins measured after 4 hrs by Amplex red and horseradish peroxidase based fluorescence assay | Homo sapiens | 52 | single protein format | Scientific Literature | ||
2. | ALA5166383 | A | Apparent permeability across apical to basolateral membrane in MDCK-MDR1 cells by LC-MS/MS analysis | Canis lupus familiaris | 46 | cell-based format | Scientific Literature | ||
3. | ALA5166384 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in MDCK-MDR1 cells | Canis lupus familiaris | 46 | cell-based format | Scientific Literature | ||
4. | ALA5166393 | B | Inhibition of full length human DAO transfected in CHO-K1 cells incubated for 30 mins by Amplex red and horseradish peroxidase based fluorescence assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
5. | ALA5166394 | B | Inhibition of full length mouse DAO transfected with CHO-K1 cells incubated for 30 mins by Amplex red and horseradish peroxidase based fluorescence assay | Mus musculus | 46 | cell-based format | Scientific Literature | ||
6. | ALA5166395 | P | Lipophilicity, log D of compound by chromatographic method | 8 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA5166396 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM measured upto 40 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | microsome format | Scientific Literature | ||
8. | ALA5166397 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance at 1 uM measured upto 40 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 8 | microsome format | Scientific Literature | ||
9. | ALA5166398 | A | Metabolic stability in human hepatocyte assessed as intrinsic clearance measured per million cells at 1 uM measured over 120 mins by LC-MS/MS analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
10. | ALA5166399 | A | Metabolic stability in mouse hepatocyte assessed as intrinsic clearance measured per million cells at 1 uM measured over 120 mins by LC-MS/MS analysis | Mus musculus | 8 | cell-based format | Scientific Literature |