| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5148065 | F | Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence of IBMX by cAMP assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 2. | ALA5148066 | A | Metabolic stability in rat liver microsomes assessed as compound remaining at 1 uM incubated for 30 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 15 | microsome format | Scientific Literature | ||
| 3. | ALA5148067 | P | Aqueous solubility of the compound in pH 1.2 JP1 fluid measured after 4 hrs by HPLC-UV analysis | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA5148068 | P | Aqueous solubility of the compound in pH 6.8 JP2 fluid measured after 4 hrs by HPLC-UV analysis | 14 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA5148070 | A | Cmax in Sprague-Dawley rat at 5 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 6. | ALA5148071 | A | AUClast in Sprague-Dawley rat at 5 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 7. | ALA5148072 | P | Distribution coefficient, log D of compound in 1-octanol and aqueous phosphate buffered saline at pH 7.4 incubated for 30 mins by HPLC-MS analysis | 5 | small-molecule physicochemical format | Scientific Literature |
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