| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5149726 | B | Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ethyl isopropyl amiloride by BCECF-AM dye based fluorescence assay | Homo sapiens | 46 | ALA5143744 | cell-based format | Scientific Literature | |
| 2. | ALA5149727 | B | Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ethyl isopropyl amiloride by BCECF-AM dye based fluorescence assay | Rattus norvegicus | 43 | ALA5143744 | cell-based format | Scientific Literature | |
| 3. | ALA5149766 | F | In vivo inhibition of NEH3 in Sprague-Dawley rat assessed as reduction in sodium excretion in urine at 0.1 to 3 mg/kg, po administered via gavage measured after 16 hrs by ion chromatography | Rattus norvegicus | 6 | ALA5143744 | organism-based format | Scientific Literature | |
| 4. | ALA5149767 | F | In vivo inhibition of NEH3 in Sprague-Dawley rat assessed as increase in fecal water content at 0.1 to 3 mg/kg, po administered via gavage measured after 6 hrs | Rattus norvegicus | 6 | ALA5143744 | organism-based format | Scientific Literature | |
| 5. | ALA5149769 | A | Drug recovery in Sprague-Dawley rat feces at 0.3 mg/kg, po administered via gavage measured after 64 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5143744 | organism-based format | Scientific Literature | |
| 6. | ALA5149772 | A | Drug metabolism in Sprague-Dawley rat feces at 0.3 mg/kg, po administered via gavage measured after 64 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA5143744 | organism-based format | Scientific Literature | |
| 7. | ALA5149774 | A | Cmax in Sprague-Dawley rat at 30 mg/kg, po administered via gavage by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA5143744 | organism-based format | Scientific Literature | |
| 8. | ALA5149775 | A | Drug metabolism in Sprague-Dawley rat at 30 mg/kg, po administered via gavage by LC-MS/MS analysis | Rattus norvegicus | 6 | ALA5143744 | organism-based format | Scientific Literature | |
| 9. | ALA5149776 | T | Inhibition of human ERG at 10 uM relative to control | Homo sapiens | 6 | ALA5143744 | assay format | Scientific Literature |
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