# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5155831 | B | Inhibition of FAK (unknown origin) using Fluorescein-Poly GAT as substrate incubated for 30 mins and measured after 60 mins by Lanthascreen assay | Homo sapiens | 49 | single protein format | Scientific Literature | ||
2. | ALA5155832 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining incubated for 120 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | microsome format | Scientific Literature | ||
3. | ALA5155833 | A | Metabolic stability in human liver microsomes assessed as half-life incubated for 120 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | microsome format | Scientific Literature | ||
4. | ALA5155834 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance incubated for 120 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 8 | microsome format | Scientific Literature | ||
5. | ALA5155835 | P | Aqueous solubility of compound | 8 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA5155836 | B | Inhibition of FAK (unknown origin) at 1 uM incubated for 40 mins in presence of Mg/ATP mix relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA5155837 | B | Inhibition of LRRK2 (unknown origin) at 1 uM incubated for 40 mins in presence of Mg/ATP mix relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA5155838 | B | Inhibition of CLK4 (unknown origin) at 1 uM incubated for 40 mins in presence of Mg/ATP mix relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA5155839 | B | Inhibition of Fes (unknown origin) at 1 uM incubated for 40 mins in presence of Mg/ATP mix relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA5155840 | B | Inhibition of CLK1 (unknown origin) at 1 uM incubated for 40 mins in presence of Mg/ATP mix relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA5155841 | B | Inhibition of STK33 (unknown origin) at 1 uM incubated for 40 mins in presence of Mg/ATP mix relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA5155842 | B | Inhibition of ALK (unknown origin) at 1 uM incubated for 40 mins in presence of Mg/ATP mix relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA5155845 | B | Inhibition of FAK in human PA-1 cells assessed as suppression of FAK autophosphorylation at 10 nM and measured by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5155846 | B | Inhibition of FAK in human PA-1 cells assessed as suppression of AKT autophosphorylation at 1.25 to 5 microM and measured by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA5155847 | B | Inhibition of FAK in human PA-1 cells assessed as suppression of Src autophosphorylation at 5 microM and measured by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA5155848 | F | Inhibition of migration of human PA-1 cells at 2 uM measured after 24 hrs by Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA5155849 | F | Inhibition of invasion of human PA-1 cells at 2 uM measured after 24 hrs by Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA5155850 | F | Down-regulation of MMP-2 expression in human PA-1 cells at 2 uM measured after 0.5 to 6 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA5155851 | F | Down-regulation of MMP-9 expression in human PA-1 cells at 2 uM measured after 0.5 to 6 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA5155852 | A | Half-life in Sprague-Dawley rat at 20 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature |