# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5157984 | F | Agonist activity at S1P1 receptor (unknown origin) expressed in PathHunter CHO-K1 EDG1 beta-arrestin cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by measuring chemiluminescence signal by microplate reader method | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
2. | ALA5157985 | F | Agonist activity at S1P1 receptor (unknown origin) expressed in PathHunter HEK 293 EDG1 Total GPCR Internalization cells assessed as receptor internalization incubated for 90 mins by measuring chemiluminescence signal by microplate reader method | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
3. | ALA5157986 | F | Agonist activity at S1P3 receptor (unknown origin) expressed in PathHunter CHO-K1 EDG1 beta-arrestin cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by measuring chemiluminescence signal by microplate reader method | Homo sapiens | 65 | cell-based format | Scientific Literature | ||
4. | ALA5157987 | A | Inhibition of CYP1A2 (unknown origin) at 10 uM preincubated for 10 mins followed by addition of NADPH measured after 10 mins by microplate reader assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
5. | ALA5157988 | A | Inhibition of CYP2C19 (unknown origin) at 10 uM preincubated for 10 mins followed by addition of NADPH measured after 20 mins by microplate reader assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
6. | ALA5157989 | A | Inhibition of CYP2D6 (unknown origin) at 10 uM preincubated for 10 mins followed by addition of NADPH measured after 30 mins by microplate reader assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
7. | ALA5157990 | A | Inhibition of CYP2C9 (unknown origin) at 10 uM preincubated for 10 mins followed by addition of NADPH measured after 30 mins by microplate reader assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
8. | ALA5157991 | A | Inhibition of CYP3A4 (unknown origin) at 10 uM preincubated for 10 mins followed by addition of NADPH measured after 10 mins by microplate reader assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
9. | ALA5157992 | A | Microsomal stability in human microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by addition of NADPH regenerating system measured after 30 mins by LC-MS/MS analysis | Homo sapiens | 52 | microsome format | Scientific Literature | ||
10. | ALA5157993 | A | Microsomal stability in mouse microsomes assessed as parent compound remaining at 1 uM preincubated for 5 mins followed by addition of NADPH regenerating system measured after 30 mins by LC-MS/MS analysis | Mus musculus | 51 | microsome format | Scientific Literature |