# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5149372 | F | Induction of cell death in human HepG2 cells measured after 48 hrs by Annexin V-FITC/PI double staining based flow cytometry analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
2. | ALA5149373 | F | Antiproliferative activity against human HepG2 cells assessed as inhibition of clone formation pretreated for 48 hrs followed by replacement with drug free medium every 3 days for 10 days by crystalline violet staining based assay | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
3. | ALA5149374 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
4. | ALA5149375 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by CCK-8 assay | Homo sapiens | 72 | ALA5143734 | cell-based format | Scientific Literature | |
5. | ALA5149376 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability by CCK-8 assay | Homo sapiens | 72 | ALA5143734 | cell-based format | Scientific Literature | |
6. | ALA5149377 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by CCK-8 assay | Homo sapiens | 72 | ALA5143734 | cell-based format | Scientific Literature | |
7. | ALA5149378 | F | Cytotoxicity against human PC-3M cells assessed as reduction in cell viability by CCK-8 assay | Homo sapiens | 72 | ALA5143734 | cell-based format | Scientific Literature | |
8. | ALA5149379 | F | Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability by CCK-8 assay | Homo sapiens | 72 | ALA5143734 | cell-based format | Scientific Literature | |
9. | ALA5149380 | F | Antiinvasive activity in human HepG2 cells assessed as inhibition of cell invasion measured after 24 hrs by crystal violet staining based transwell assay | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
10. | ALA5149381 | F | Antimigratory activity against human HepG2 cells assessed as reduction in cell migration measured after 24 hrs by crystal violet staining based transwell assay | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
11. | ALA5149382 | F | Antiproliferative activity against human HepG2 cells at 0.125 to 0.5 uM incubated for 48 hrs | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
12. | ALA5149383 | F | Induction of ferroptosis in human HepG2 cells assessed as decrease in GPX4 mRNA expression measured after 6 to 12 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
13. | ALA5149384 | F | Induction of ferroptosis in human HepG2 cells assessed as increase in ACSL4 mRNA expression at 0.5 to 1.0 uM by qRT-PCR analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
14. | ALA5149385 | F | Induction of ferroptosis in human HepG2 cells assessed as increase in ACSL4 mRNA expression measured after 6 to 36 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
15. | ALA5149386 | F | Induction of ferroptosis in human HepG2 cells assessed as decrease in GPX4 mRNA expression measured after 36 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
16. | ALA5149387 | F | Induction of ferroptosis in human HepG2 cells assessed as log2 fold decrease in GPX4 mRNA expression by qRT-PCR analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
17. | ALA5149388 | F | Induction of ferroptosis in human HepG2 cells assessed as log2 fold increase in ACSL4 mRNA expression by qRT-PCR analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
18. | ALA5149389 | F | Induction of ferroptosis in human HepG2 cells assessed as increase in ACSL4 protein expression at 2 uM by Western blot analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
19. | ALA5149390 | F | Induction of ferroptosis in human HepG2 cells assessed as decrease in GPX4 protein expression at 2 uM measured after 6 hrs by Western blot analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature | |
20. | ALA5149391 | F | Induction of ferroptosis in human HepG2 cells assessed as decrease in GPX4 protein expression at 2 uM by Western blot analysis | Homo sapiens | 1 | ALA5143734 | cell-based format | Scientific Literature |