| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5168438 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by cell titer glo luminescent assay | Homo sapiens | 33 | ALA5154937 | cell-based format | Scientific Literature | |
| 2. | ALA5168439 | B | Inhibition of recombinant human NAMPT incubated for 60 mins by colorimetric assay | Homo sapiens | 20 | ALA5154937 | single protein format | Scientific Literature | |
| 3. | ALA5168440 | B | Substrate activity at recombinant human NQO1 assessed as reduction in NADPH level measured per umol of NQO1 at 10 uM in presence of NADPH by NADPH recycling assay | Homo sapiens | 20 | ALA5154937 | single protein format | Scientific Literature | |
| 4. | ALA5168442 | F | Antiproliferative activity against human A549/Taxol cells assessed as inhibition of cell growth measured after 72 hrs by cell titer glo luminescent assay | Homo sapiens | 10 | ALA5154937 | cell-based format | Scientific Literature | |
| 5. | ALA5168443 | T | Antiproliferative activity against human L02 cells assessed as inhibition of cell growth measured after 72 hrs by cell titer glo luminescent assay | Homo sapiens | 10 | ALA5154937 | cell-based format | Scientific Literature | |
| 6. | ALA5168444 | T | Selectivity ratio of IC50 for human L02 cells to IC50 for human A549/Taxol cells | 10 | ALA5154937 | assay format | Scientific Literature | ||
| 7. | ALA5168445 | F | Antiproliferative activity against human A549/Taxol cells assessed as inhibition of cell growth pretreated with NQO1 inhibitor, dicumarol followed by compound addition and measured after for 72 hrs by cell titer glo luminescent assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 8. | ALA5168446 | F | Antiproliferative activity against human A549/Taxol cells assessed as inhibition of cell growth pretreated with N-acetyl-L-cysteine followed by compound addition and measured after 72 hrs by cell titer glo luminescent assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 9. | ALA5168447 | F | Antiproliferative activity against human A549/Taxol cells assessed as inhibition of cell growth pretreated with nicotinamide mononucleotide followed by compound addition and measured after 72 hrs by cell titer glo luminescent assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 10. | ALA5168448 | F | Antiproliferative activity against human A549/Taxol cells assessed as inhibition of cell growth pretreated with nicotinamide mononucleotide, dicumarol, N-acetyl-L-cysteine followed by compound addition and measured after 72 hrs by cell titer glo luminescent assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 11. | ALA5168449 | F | Inhibition of NAD+ biosynthesis in human A549/Taxol cells assessed as decrease in cellular NAD+ level at 15 uM by WST-8 assay | Homo sapiens | 3 | ALA5154937 | cell-based format | Scientific Literature | |
| 12. | ALA5168450 | F | Inhibition of NAD+ biosynthesis in human A549/Taxol cells assessed as decrease in cellular NAD+ level at 15 uM pretreated with NQO1 inhibitor, dicumarol for 30 mins followed by compound addition by WST-8 assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 13. | ALA5168451 | F | Inhibition of NAD+ biosynthesis in human A549/Taxol cells assessed as decrease in cellular NAD+ level at 15 uM pretreated with nicotinamide mononucleotide for 1 hr followed by compound addition by WST-8 assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 14. | ALA5168452 | F | Induction of ROS production in human A549/Taxol cells incubated for 3 hrs by DCFH-DA staining based flow cytometry analysis | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 15. | ALA5168453 | F | Induction of ROS production in human A549/Taxol cells at 15 uM pretreated with NQO1 inhibitor, dicumarol for 30 mins followed by compound addition and measured after 3 hrs by DCFH-DA staining based flow cytometry analysis | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 16. | ALA5168454 | F | Induction of ROS production in human A549/Taxol cells at 15 uM pretreated with N-acetyl-L-cysteine for 1 hr followed by compound addition and measured after 3 hrs by DCFH-DA staining based flow cytometry analysis | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 17. | ALA5168455 | F | Induction of DNA damage in human A549/Taxol cells at 15 uM measured after 6 hrs by alkaline Comet assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 18. | ALA5168456 | F | Induction of DNA damage in human A549/Taxol cells at 15 uM pretreated with NQO1 inhibitor, dicumarol for 30 mins followed by compound addition and measured after 6 hrs by alkaline Comet assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 19. | ALA5168457 | F | Induction of DNA damage in human A549/Taxol cells at 15 uM pretreated with N-acetyl-L-cysteine for 1 hr followed by compound addition and measured after 6 hrs by alkaline Comet assay | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature | |
| 20. | ALA5168458 | F | Induction of apoptosis in human A549/Taxol cells assessed as increase in total apoptotic cells incubated for 24 hrs by Annexin V-FITC and propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA5154937 | cell-based format | Scientific Literature |
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