| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5121010 | B | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC4 expressed in Escherichia coli (BL21) DE3 pLysS cells assessed as residual activity at 50 uM using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 2. | ALA5121011 | B | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC8 expressed in Escherichia coli (BL21) DE3 pLysS cells assessed as residual activity at 50 uM using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 3. | ALA5121012 | B | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC4 expressed in Escherichia coli (BL21) DE3 pLysS cells using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 4. | ALA5121013 | B | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC8 expressed in Escherichia coli (BL21) DE3 pLysS cells using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 5. | ALA5121019 | B | Inhibition of human VEGFR2 in HUVEC cells assessed as reduction in VEGFR2 phosphorylation at 10 uM incubated for 30 mins by anti-phospho VEGF Tyr 1175 antibody based assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA5121021 | T | Cytotoxicity against HUVEC cells assessed as reduction in cell viability after 96 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA5121022 | B | Inhibition of human VEGFR2 in HUVEC cells assessed as reduction in VEGFR2 phosphorylation incubated for 30 mins by anti-phospho VEGF Tyr 1175 antibody based assay | Homo sapiens | 5 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!