# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5123435 | B | Inhibition of N-terminal DYKDDDD-tagged truncated FAK (376 to 1052 residues) (unknown origin) expressed in Sf21 insect cells at 0.5 uM using TK as substrate in presence of ATP measured after 50 mins by HTRF assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
2. | ALA5123436 | B | Inhibition of N-terminal DYKDDDD-tagged truncated FAK (376 to 1052 residues) (unknown origin) expressed in Sf21 insect cells at 0.1 uM using TK as substrate in presence of ATP measured after 50 mins by HTRF assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
3. | ALA5123437 | B | Inhibition of N-terminal DYKDDDD-tagged truncated FAK (376 to 1052 residues) (unknown origin) expressed in Sf21 insect cells using TK as substrate in presence of ATP measured after 50 mins by HTRF assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
4. | ALA5123438 | B | Protac activity at CRBN E3 ligase/FAK in human A549 cells assessed as induction of FAK protein degradation at 0.1 uM incubated for 12 hrs by Western blot analysis relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
5. | ALA5123439 | B | Protac activity at CRBN E3 ligase/FAK in human A549 cells assessed as induction of FAK protein degradation at 0.01 uM incubated for 12 hrs by Western blot analysis relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
6. | ALA5123440 | B | Potency index, ratio of test compound IC50 to TAE-226 IC50 for inhibition of N-terminal DYKDDDD-tagged truncated FAK (376 to 1052 residues) (unknown origin) expressed in Sf21 insect cells using TK as substrate in presence of ATP measured after 50 mins by HTRF assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
7. | ALA5123441 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 12 | cell-based format | Scientific Literature |