The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5138978 B Displacement of Alexa Fluor labelled Tracer-314 from human N-terminal GST-tagged mTOR incubated for 1 hr by TR-FRET assay Homo sapiens 23 single protein format Scientific Literature 2. ALA5138979 B Inhibition of PI3Kalpha in rat Rat1 cells assessed as reduction in phosphorylation of AKT at Ser473 residue incubated for 1 hr by cellular assay Rattus norvegicus 37 cell-based format Scientific Literature 3. ALA5138980 B Inhibition of PI3Kbeta in rat Rat1 cells assessed as reduction in phosphorylation of AKT at Ser473 residue incubated for 1 hr by cellular assay Rattus norvegicus 37 cell-based format Scientific Literature 4. ALA5138981 B Inhibition of PI3Kdelta in rat Rat1 cells assessed as reduction in phosphorylation of AKT at Ser473 residue incubated for 1 hr by cellular assay Rattus norvegicus 37 cell-based format Scientific Literature 5. ALA5138984 B Binding affinity to tubulin in human A2058 cells assessed as condensed DNA score at 5 uM measured after 24 hrs by DiffQuick staining based microscopic analysis Homo sapiens 11 cell-based format Scientific Literature 6. ALA5138985 A Half life in Beagle dog at 5.4 mg/kg, po measured upto 24 hrs using PVP-ASD form of sample by LC-MS/MS analysis Canis lupus familiaris 1 organism-based format Scientific Literature 7. ALA5138986 A Dose normalized AUC in Sprague-Dawley rat at 3 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 8. ALA5138987 F Induction of cell cycle arrest in human A2780 cells assessed as G2/M marker expression level at 30 uM measured after 6 hr by immunofluorescence staining method Homo sapiens 2 cell-based format Scientific Literature 9. ALA5138988 A Brain to blood ratio in OF1 mouse at 1 mg/kg, iv measured at 5 mins post dose by LC-MS/MS analysis Mus musculus 11 organism-based format Scientific Literature 10. ALA5138989 A Brain to blood ratio in OF1 mouse at 1 mg/kg, iv measured at 1 hr post dose by LC-MS/MS analysis Mus musculus 11 organism-based format Scientific Literature 11. ALA5138990 A Drug concentration in OF1 mouse blood at 1 mg/kg, iv measured at 5 mins post dose by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 12. ALA5138991 A Drug concentration in OF1 mouse blood at 1 mg/kg, iv measured at 1 hr post dose by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 13. ALA5138992 A Drug concentration in OF1 mouse brain at 1 mg/kg, iv measured at 5 mins post dose by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 14. ALA5138993 A Drug concentration in OF1 mouse brain at 1 mg/kg, iv measured at 1 hr post dose by LC-MS/MS analysis Mus musculus 2 organism-based format Scientific Literature 15. ALA5138994 A Stability in mouse liver microsomes assessed as hepatic extraction preincubated for 3 mins followed by NADPH addition and measured after 60 mins Mus musculus 2 microsome format Scientific Literature 16. ALA5138995 A Stability in rat liver microsomes assessed as hepatic extraction preincubated for 3 mins followed by NADPH addition and measured after 60 mins Rattus norvegicus 3 microsome format Scientific Literature 17. ALA5138996 A Stability in human liver microsomes assessed as hepatic extraction preincubated for 3 mins followed by NADPH addition and measured after 60 mins Homo sapiens 3 microsome format Scientific Literature 18. ALA5138997 A Clearance in Sprague-Dawley rat at 3 mg/kg, po or iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 3 organism-based format Scientific Literature 19. ALA5138998 A Volume of distribution at steady state in Sprague-Dawley rat at 3 mg/kg, po or iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 3 organism-based format Scientific Literature 20. ALA5138999 A Half life in Sprague-Dawley rat at 3 mg/kg, po or iv measured upto 24 hrs by LC-MS/MS analysis Rattus norvegicus 3 organism-based format Scientific Literature