# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5162302 | Binding | Inhibition of wild type human GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 cells incubated for 30 mins in presence of ATP by HTRF analysis | Homo sapiens | 21 | ALA5154811 | cell-based format | Scientific Literature | |
2. | ALA5162303 | Binding | Inhibition of wild type human N-terminal GST tagged EGFR (669 to 1210 residues) expressed in Sf21 insect cells incubated for 30 mins in presence of ATP by HTRF analysis | Homo sapiens | 22 | ALA5154811 | cell-based format | Scientific Literature | |
3. | ALA5162304 | Binding | Selectivity ratio of IC50 for wild type human N-terminal GST tagged EGFR (669 to 1210 residues) expressed in Sf21 insect cells to IC50 for wild type human GST-tagged HER2 (676 to end residues) expressed in baculovirus infected Sf9 cells | Homo sapiens | 21 | ALA5154811 | cell-based format | Scientific Literature | |
4. | ALA5162305 | Functional | Antiproliferative activity against human NCI-N87 cells assessed as inhibition of cell growth incubated for 72 hrs by Celltiter-Glo assay | Homo sapiens | 22 | ALA5154811 | cell-based format | Scientific Literature | |
5. | ALA5162306 | Functional | Antiproliferative activity against human BT-474 cells assessed as inhibition of cell growth incubated for 72 hrs by Celltiter-Glo assay | Homo sapiens | 22 | ALA5154811 | cell-based format | Scientific Literature |