# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5112574 | B | Inhibition of recombinant human sEH using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as substrate incubated for 5 mins | Homo sapiens | 19 | single protein format | Scientific Literature | ||
2. | ALA5112575 | B | Inhibition of mouse sEH in using using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as substrate incubated for 5 mins | Mus musculus | 19 | single protein format | Scientific Literature | ||
3. | ALA5112576 | A | Microsomal stability in human recombinant microsomes assessed as parent compound remaining in the presence of NADPH measured after 60 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 18 | microsome format | Scientific Literature | ||
4. | ALA5112577 | A | Microsomal stability in mouse microsomes assessed as parent compound remaining in the presence of NADPH measured after 60 mins by UPLC-MS/MS analysis relative to control | Mus musculus | 18 | microsome format | Scientific Literature | ||
5. | ALA5112578 | P | Solubility of the compound in PBS buffer incubated for 2 hrs by nephelometry reader analysis | 9 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA5112579 | F | Cytotoxicity against human SH-SY5Y cells assessed as cell death incubated for 24 hrs by propidium iodide fluorescence stain assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
7. | ALA5112580 | F | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA5112581 | A | Inhibition of human recombinant CYP2C9 at 10 uM using 7-methoxy-4(trifluoromethyl coumarin) as a substrate preincubated for 5 mins followed by substrate addition by fluorescence plate reader analysis relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
9. | ALA5112583 | A | Inhibition of human recombinant CYP2C19 using 3-cyano-7-ethoxycoumarin as a substrate preincubated for 5 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
10. | ALA5112584 | A | Inhibition of human recombinant CYP2C19 at 10 uM using 7-BFC and DBF as a substrate preincubated for 5 mins followed by substrate addition by fluorescence plate reader analysis relative to control | Homo sapiens | 8 | assay format | Scientific Literature |