# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5121196 | B | Antagonist activity at ERalpha (unknown origin) | Homo sapiens | 19 | ALA5120749 | single protein format | Scientific Literature | |
2. | ALA5121197 | B | Antagonist activity at ERbeta (unknown origin) | Homo sapiens | 19 | ALA5120749 | single protein format | Scientific Literature | |
3. | ALA5121198 | B | Relative binding affinity to ERalpha (unknown origin) | Homo sapiens | 19 | ALA5120749 | single protein format | Scientific Literature | |
4. | ALA5121199 | B | Relative binding affinity to ERbeta (unknown origin) | Homo sapiens | 19 | ALA5120749 | single protein format | Scientific Literature | |
5. | ALA5121200 | F | Antiproliferative activity against human MCF7 cells | Homo sapiens | 14 | ALA5120749 | cell-based format | Scientific Literature | |
6. | ALA5121201 | F | Antiproliferative activity against human MDA-MB-231 cells | Homo sapiens | 14 | ALA5120749 | cell-based format | Scientific Literature | |
7. | ALA5121202 | U | Selectivity index, ratio IC50 for antiproliferative activity against human MDA-MB-231 cells over IC50 for antiproliferative activity against human MCF7 cells | 14 | ALA5120749 | cell-based format | Scientific Literature | ||
8. | ALA5121203 | F | Antiproliferative activity against human MRC5 cells | Homo sapiens | 14 | ALA5120749 | cell-based format | Scientific Literature | |
9. | ALA5121204 | B | Antagonist activity at ERalpha in human MCF7 cells assessed as downregulation of ERalpha | Homo sapiens | 14 | ALA5120749 | cell-based format | Scientific Literature | |
10. | ALA5121205 | B | Antagonist activity at progesterone receptor in human MCF7 cells | Homo sapiens | 14 | ALA5120749 | cell-based format | Scientific Literature | |
11. | ALA5121206 | F | Antiproliferative activity against human Ishikawa cells | Homo sapiens | 14 | ALA5120749 | cell-based format | Scientific Literature | |
12. | ALA5121209 | B | Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of p-Raf-1 activation at 1 to 10 nM measured after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA5120749 | cell-based format | Scientific Literature | |
13. | ALA5121210 | B | Antagonist activity at ERalpha in human MCF7 cells assessed as inhibition of p-ERK1/2 activation at 1 to 10 nM measured after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA5120749 | cell-based format | Scientific Literature | |
14. | ALA5121213 | B | Antagonist activity at ERalpha in human MCF7 cells assessed as effect on total levels of Raf-1 at 1 to 10 nM measured after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA5120749 | cell-based format | Scientific Literature | |
15. | ALA5121214 | B | Antagonist activity at ERalpha in human MCF7 cells assessed as effect on total levels of ERK1/2 at 1 to 10 nM measured after 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA5120749 | cell-based format | Scientific Literature | |
16. | ALA5121217 | F | Downregulation of hERE gene transcription expression in human MCF7 cells at 1 to 10 nM measured by luciferase reporter gene assay | Homo sapiens | 3 | ALA5120749 | cell-based format | Scientific Literature | |
17. | ALA5121218 | F | Downregulation of hERE gene transcription expression in human MCF7 cells at 1 to 10 nM measured by luciferase reporter gene assay | Homo sapiens | 3 | ALA5120749 | cell-based format | Scientific Literature | |
18. | ALA5121220 | F | Induction of cell cycle arrest in human MCF7 cells assessed as cell accumulation at G0/G1 phase at 1 nM after 24 hrs | Homo sapiens | 15 | ALA5120749 | cell-based format | Scientific Literature | |
19. | ALA5121221 | F | Induction of cell cycle arrest in human MCF7 cells assessed as cell accumulation at G0/G1 phase at 10 nM after 24 hrs | Homo sapiens | 3 | ALA5120749 | cell-based format | Scientific Literature | |
20. | ALA5121223 | F | Induction of cell cycle arrest in human MCF7 cells assessed as cell accumulation at S phase at 1 nM after 24 hrs | Homo sapiens | 15 | ALA5120749 | cell-based format | Scientific Literature |