# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5163692 | B | Inhibition of human cytomegalovirus pHAR-UL89C expressed in Escherichia coli Rosette using Digoxigenin-labeled 5'-taatcgccttgcagcacatccccattcgccagctggcgtaatagcgaagaggcccgca ssDNA as substrate at 5 uM preincubated for 15 mins followed by substrate addition for 30 mins by plate reader assay relative to control | Cytomegalovirus | 57 | ALA5154836 | assay format | Scientific Literature | |
2. | ALA5163693 | B | Inhibition of human cytomegalovirus pHAR-UL89C expressed in Escherichia coli Rosette using Digoxigenin-labeled 5'-taatcgccttgcagcacatccccattcgccagctggcgtaatagcgaagaggcccgca ssDNA as substrate preincubated for 15 mins followed by substrate addition for 30 mins by plate reader assay | Cytomegalovirus | 38 | ALA5154836 | assay format | Scientific Literature | |
3. | ALA5163694 | B | Binding affinity to human cytomegalovirus pUL89 assessed as change in melting temperature at 20 uM preincubated for 15 mins by Thermal shift assay | Cytomegalovirus | 57 | ALA5154836 | single protein format | Scientific Literature | |
4. | ALA5163695 | F | Antiviral activity against human cytomegalovirus expressing ADCREGFP infected in HFF cells assessed as inhibition in viral replication by measuring GFP fluorescence incubated for 168 hrs by cell based assay | Cytomegalovirus | 10 | ALA5154836 | organism-based format | Scientific Literature | |
5. | ALA5163696 | T | Cytotoxicity against HFF cells assessed as cell viability incubated for 168 hrs by MTS-based Cell Titer assay | Homo sapiens | 10 | ALA5154836 | cell-based format | Scientific Literature | |
6. | ALA5163697 | T | Selectivity index, ratio of CC50 for cytotoxicity against HFF cells to EC50 for antiviral activity against human cytomegalovirus expressing ADCREGFP infected in HFF cells | 10 | ALA5154836 | cell-based format | Scientific Literature |